ASH Poster Walks

ASH Poster Walk on Beyond Acute Vaso-Occlusion: Emerging Mechanisms and Phenotypes of Chronic Pain in Sickle Cell Disease Hosted by Blood Red Cells & Iron

Chronic pain is one of the most common and disabling complications of sickle cell disease, yet it remains highly variable between patients and is not fully explained by traditional markers of disease severity. Recent research has expanded our understanding of the biological, neurological, and clinical mechanisms that contribute to chronic pain, including central sensitization, neurovascular dysfunction, patient-reported outcomes, neuroimaging, and novel treatment approaches. This Poster Walk will bring together emerging research that highlights these advances and their potential to improve patient care. By showcasing innovative studies from basic, translational, and clinical investigators, the session will provide attendees with a broad overview of current progress, encourage discussion across disciplines, and identify opportunities for future research and collaboration. Participants will leave with a better understanding of the evolving science of chronic pain in sickle cell disease and how these findings may influence future clinical practice, research, and therapeutic development.

Chair:

Daniel Sop, PhD

Richmond, VA

Patrick Gallagher, MD

Columbus, OH

ASH Poster Walk on Beyond the Algorithm: The Next Era of Artificial Intelligence in Hematology

Artificial intelligence is rapidly expanding across all facets of hematology, including diagnosis, image analysis, risk stratification, prognostication, clinical decision support, therapeutic selection, clinical trial matching, drug discovery, and healthcare delivery. Traditional machine learning, deep learning, computer vision, and natural language processing continue to generate important advances, while the emergence of generative AI, large language models, AI agents, and agentic frameworks is creating new opportunities to synthesize complex data and support increasingly sophisticated clinical and research workflows. This Poster Walk will highlight cutting-edge applications of AI across malignant and classical hematology, with particular attention to generative AI and emerging agentic systems.

Chair:

David Swoboda, MD

Tampa, FL

ASH Poster Walk on Emerging Toxicities and Predictors in T-Cell–Redirecting Therapies Hosted by Blood Immunology & Cellular Therapy

CAR T-cell therapies and bispecific antibodies have transformed the treatment of lymphoma and multiple myeloma. As their use expands, the toxicity landscape is evolving beyond cytokine release syndrome and conventional ICANS. Prolonged cytopenias, impaired immune reconstitution, and severe or opportunistic infections further contribute to late morbidity and non-relapse mortality. Particular concern is emerging around delayed, persistent, and potentially progressive neurologic complications occurring beyond the conventional timeframe and clinical spectrum of ICANS. These include movement disorders, cognitive impairment, peripheral neuropathies, and other late neurotoxicity syndromes whose incidence, mechanisms, natural history, and optimal management remain poorly defined. Despite growing recognition of these complications, reliable predictors remain limited. Available risk scores and biomarkers primarily address acute CRS and ICANS and frequently lack validation across diseases, therapeutic platforms, and clinical settings.

This Poster Walk will highlight emerging toxicities and their clinical, biological, and treatment-related predictors. Particular attention will be given to artificial intelligence and machine-learning approaches that can integrate clinical, inflammatory, metabolic, immunologic, product-related, and longitudinal data, uncover complex risk patterns, and generate dynamic prediction models beyond individual biomarkers. These models could enable personalized surveillance, preventive interventions, outpatient treatment, early discharge, and timely escalation of care.

Chair:

Mirko Farina, MD, PhD

Brescia, Italy

Willem Fibbe, MD, PhD

Leiden, Netherlands

ASH Poster Walk on Innovations in Hemostasis and Thrombosis Clinical Research Design Hosted by Blood Vessels, Thrombosis & Hemostasis

This Poster Walk will address the critical need of strengthening understanding and application of rigorous, clinical trial design and statistical methodology for classical hematology research. Using hemostasis and thrombosis studies, the Poster Walk will showcase how trial design, epidemiologic approaches, and advanced statistical methods can improve the quality, interpretability, and impact of clinical research. The Walk will feature three posters with the author providing an 8-minute presentation, followed by a 5-minute expert methodological discussion led by an invited biostatistician. These commentaries will clarify the rationale for key design and analytic decisions, highlight innovative approaches, and translate technical concepts into practical lessons for clinicians, investigators, and trainees. 

Chair:

Lisa Baumann Kreuziger, MD, MS

Milwaukee, 

Keith McCrae, MD

Cleveland, 

ASH Poster Walk on Leukemia in Latin America: Outcomes and Access to Diagnostics and Therapies Hosted by Blood Global Hematology

Leukemia outcomes in Latin America are shaped not only by disease biology, but also by profound variation in access to timely diagnosis, molecular testing, supportive care, novel therapies, transplantation, and clinical trials. Despite the region’s diverse population, Latin American patients remain underrepresented in major datasets, and differences in treatment delivery and survival are often obscured when evidence is derived primarily from high-income settings. This Poster Walk will highlight emerging studies that define these gaps, evaluate real-world outcomes, and present scalable strategies to improve diagnostic and therapeutic access across the region.

This Poster Walk will benefit investigators by consolidating perspectives on epidemiology, health-system barriers, genomic characterization, treatment availability, and implementation science. By comparing experiences across countries and institutions, the selected posters can identify shared challenges while providing opportunities for collaboration. The interactive format will allow attendees to discuss which interventions are transferable, how locally generated data can guide policy and clinical practice, and how international collaborations can be structured. Participants will leave with a clearer understanding of leukemia care in Latin America, practical models for expanding precision diagnostics and research infrastructure, and opportunities to develop collaborations that improve access and outcomes for these patients.

Chair:

Samuel Urrutia, MD, MS

St. Louis, 

Jorge Cortes, MD

Birmingham, 

ASH Poster Walk on New Developments in Targeted Therapies for Myeloid Malignancies Hosted by Blood Neoplasia

Molecularly targeted approaches to myeloid malignancies have begun to impact clinical practice.  Specifically targeted therapies including IDH inhibitors, menin inhibitors, and new strategies directed at NPM1-mutated acute myeloid leukemia as well as TP53-mutated disease continue to be developed.  Even for those agents approved by regulatory agencies, optimal utilization strategies have not been defined; particularly in terms of combinatorial approaches, and earlier stage disease.  Thus, for the physician practicing in this space, the developing armamentarium can be daunting and confusing.  For the clinical investigator, understanding the landscape and the metrics for burden of proof to establish benefit  represent critical foundations.  This Poster Walk will be chosen from studies of the most interesting new molecularly-directed monotherapies as well as combinatorial studies and studies in earlier lines of treatment for established targeted agents.  The walk will provide the audience with a perspective on the current state of drug development in AML, MDS, and MPN, and provide a critical framework for assessing the data.

Chair:

Steven Gore, MD

Bethesda, MD

Jonathan Licht, MD

Grand Rapids, MI

ASH Poster Walk on Population Health and Access to Care

This Poster Walk will highlight works that investigate structural barriers impacting provision of care and approaches to extend access to optimal care for hematology patients. The walk will spotlight research that furthers efforts to overcome health disparities across populations. Featured posters will outline research that addresses and mitigates care delivery challenges, particularly those which disproportionately impact underserved or special populations. The walk will also serve to connect stakeholders in population health in hematology and facilitate discussions on the state of population health research in the field.

Chair:

Warren Fingrut, MD, MPH

Houston, TX