Hematopoiesis
For Trainees, By Trainees
Articles in Hematopoiesis are written for trainees by trainees, under the oversight of the ASH Trainee Council. The material published in Hematopoiesis is for informational purposes only. The opinions of the authors are their own and do not necessarily represent official policy of the American Society of Hematology. ASH does not recommend or endorse any specific tests, physicians, products, procedures, or opinions, and disclaims any representation, warranty, or guaranty as to the same. Reliance on any information provided in this publication is solely at your own risk.
Welcome from the Editor
Announcing Hematopoiesis, Our New ASH Trainee Council Newsletter by Trainees and for Trainees
Ajay Major, MD, MBA
Chair, ASH Trainee Council. Chief Fellow, University of Chicago, Chicago, IL (@majorajay)
The events of 2020 were unprecedented for all of us, disrupting the hematology trainee experience and the entire spectrum of medical education. For the ASH Trainee Council, creating online platforms for you, the hematologists-in-training that we represent, has become even more important as we all discovered the power of virtual spaces for learning and collaboration in the COVID era.
In response to the survey of hematology fellows that we administered and presented at the 2020 ASH Annual Meeting, which revealed significant concerns about education and career advancement due to the pandemic, we have been working over the past year to design a new dedicated publication for all budding hematologists across the training pipeline.
The ASH Trainee Council is elated to announce the inaugural issue of Hematopoiesis[1] , our new newsletter by trainees and for trainees.
Hematopoiesis is a reimagining of the former TraineE-News newsletter and is part of the Council’s broader mission to provide all levels of trainees with equitable access to educational and career development resources, including our online Hematology Review Series and virtual access to one-on-one Blood Buddy mentoring sessions at the upcoming ASH-a-Palooza.
he·mat·o·poi·e·sis
Hematopoiesis is the formation, maturation, and differentiation of all blood cells. The Trainee Council chose this name to reflect our mandate to represent the entire spectrum of hematology trainees, from medical students to housestaff to fellows, to clinicians and graduate researchers, to adult and pediatric hematologists.
Just like the bone marrow milieu where blood cells are formed, we as a community are made stronger by our diversity and by uplifting each trainee to succeed in any field of hematology. By opening Hematopoiesis to contributions by all trainees, it is our vision to create a virtual platform that transcends barriers and enables trainees to connect and learn from one another.
New trainee-authored content
In the spirit of mutual learning, we are introducing several new types of articles on Hematopoiesis that build upon our previous experience with TraineE-News, with all content generated by trainees and edited by members of the ASH Trainee Council.
In our Morning Report section, we aim to deliver high-yield didactics about both fundamental and emerging topics in hematology, such as the evolving use of measurable residual disease, the current landscape of chimeric antigen receptor T-cell therapy[1] , and the basics of peripheral blood smear interpretation for our new budding hematologists.
By expanding our Career Advice section, we can present articles on novel career paths in hematology, such as infusing patient and political advocacy into hematology practice, and practical advice from graduate students on how to begin a research career in the COVID era.
Building community around our shared experience through the medical humanities has always been an important aspect of training, even more so now as we weather the ongoing pandemic. From articles to create catharsis around the tumultuous transition between training years to promoting women in hematology, we are committed to presenting the lived experience of being a hematologist-in-training, with an eye for representing diverse voices.
Just as with TraineE-News, we will continue curating educational Case Studies for trainees, with an emphasis on increasing the variety of cases, including pediatric cases and descriptions of novel hematologic disorders.
Our new Hematopoiesis podcast
To bring our platform into the modern era, we are elated to release our first episode of Hematopoiesis, a brand-new podcast produced and curated by the ASH Trainee Council, now available on Apple podcasts, Spotify, Google podcasts, and more.
In our first episode, former Trainee Council chair Dr. Lachelle Dawn Weeks begins her three-part series on the mythical history of blood transfusion, including an interview with Professor Douglas Starr, author of Blood: An Epic History of Medicine and Commerce.
With this new podcast, we hope to bring thought-provoking educational and career-focused hematology content to you and to the community of hematology trainees around the globe, and we invite trainees interested in producing their own Hematopoiesis episodes to contact us at [email protected].
The future of Hematopoiesis
In our mission to create an organic and equitable ecosystem for hematology trainees across the training pipeline, we affirm that the most vital aspect of Hematopoiesis is you, the hematologist-in-training. In that vein, we open the doors to any and all hematology trainees to contribute to our new publication, regardless of your level of training. We seek articles or podcasts on any topic of interest to the hematology community, and we invite you to email us at [email protected] if you are interested in contributing.
We are overjoyed to finally share Hematopoiesis with all of you, and we thank you for your support, as well as the support of the American Society of Hematology, for enabling this project to come to fruition. We look forward to your feedback and invite you to read our inaugural issue.
Contribute to Hematopoiesis: Submit your case study or research article to us!
Jak in the Brain: An Incidental Hematologic Malignancy Diagnosed From a Metastatic Lung Adenocarcinoma by Next Generation Sequencing


Eric Vick, MD, PhD
John Steffes, MD
Dr. Eric Vick (@Nodlike) and Dr. John Steffes describe the case of a man with long-standing mild leukocytosis found to have a brain mass, which was biopsied confirming metastatic recurrence of lung adenocarcinoma. Notably, molecular testing to the cerebral biopsy sample demonstrated a JAK2 mutation. The mutation was also found in a peripheral blood sample prompting further workup that led to the diagnosis of myelofibrosis.
#SHEmatologists: Recap of Women in Hematology Working Group at #ASH22 and What’s
Next


Rebecca Zon, MD
Xu Han, MD, PhD
Dr. Becky Zon and Dr. Xu Han highlights the ASH Women in Hematology Working Group activities at the ASH Annual Meeting and what is next on the horizon.
Case Studies are real-life cases for trainees to share lessons learned with colleagues and peers.


Valentina Baez Sosa, MD
Kamille West-Mitchell, MD

James Kochenderfer, MD
Dr. Valentina Baez Sosa (@ValenBaezS), Dr. Kamille West-Mitchell (@Kwestmitchell), and Dr. James Kochenderfer describe the case of a 56-year-old man diagnosed with immunoglobulin A (IgA) kappa multiple myeloma who was treated with multiple chemotherapeutic regimens with a response and subsequent relapse.
Cardiac Considerations With Carfilzomib in a Patient Diagnosed With Multiple Myeloma


Aula Ramo, MD
Cortney McKay, MD

Vrushali Dabak, MD
Superior Vena Cava Syndrome


Ricardo Ortiz, MD
Adriana Malone, MD
Emergency Department Management of Sickle Cell Disease: A Point-of-Care Tool


Logan Ramsey, MD
Caroline Freiermuth, MD, MS, FACEP
Mentoring Matters: Perspectives From Basic Science Hematology Investigators (Part 1)
Xu Han, MD, PhD
Moua Yang, MD, PhD
Dr. Xu Han (@PARty4Ever_) and Dr. Moua Yang (@MouaYang21) describe how a healthy mentor-mentee relationship is critical for academic and career success.
How Research as a Medical Student Shaped My Career Trajectory


Macy L. Early, MS4
Lydia H. Pecker, MD
Macy Early, MS4 (@macy_early), with her mentor Dr. Lydia Pecker (@LydiaPecker), reflects on the ways engaging in research shaped her career trajectory and aspirations throughout medical school, as she discovered a love for sickle cell disease and healthcare delivery sciences through research in reproductive health.
I’ve registered for ASH. Now what?


Ajay Major, MD, MBA
Rebecca Zon, MD
Explore the Latest Case Studies and Articles From Hematopoiesis
A THICK PROBLEM
Dr. Valentina Baez Sosa (@ValenBaezS), Dr. Kamille West-Mitchell (@Kwestmitchell), and Dr. James Kochenderfer describe the case of a 56-year-old man diagnosed with immunoglobulin A (IgA) kappa multiple myeloma who was treated with multiple chemotherapeutic regimens with a response and subsequent relapse.
Read moreJak in the Brain: An Incidental Hematologic Malignancy Diagnosed From a Metastatic Lung Adenocarcinoma by Next Generation Sequencing
Dr. Eric Vick (@Nodlike) and Dr. John Steffes describe the case of a man with long-standing mild leukocytosis found to have a brain mass, which was biopsied confirming metastatic recurrence of lung adenocarcinoma. Notably, molecular testing to the cerebral biopsy sample demonstrated a JAK2 mutation. The mutation was also found in a peripheral blood sample prompting further workup that led to the diagnosis of myelofibrosis.
Read more#SHEmatologists: Recap of Women in Hematology Working Group at #ASH22 and What’s Next
Dr. Becky Zon and Dr. Xu Han highlights the ASH Women in Hematology Working Group activities at the ASH Annual Meeting and what is next on the horizon.
Read moreI’ve Registered for ASH. Now What?
Although the 64th ASH Annual Meeting is listed as taking place from December 10-13 in New Orleans, you will not want to miss our huge trainee-dedicated event, ASH-a-Palooza, occurring on December 9 at the extravagant Mardi Gras World! ASH-a-Palooza i...
Read moreSuperior Vena Cava Syndrome
A 33-year-old man with a previous medical history of well-controlled HIV on antiretroviral therapy and primary mediastinal large B-cell lymphoma (PMBCL) presented to the bone marrow transplant (BMT) clinic for evaluation of relapsed lymphoma. He was...
Read moreA 78-Year-Old Man with Anasarca and Chronic Kidney Disease
A man presented to his physician for evaluation of lower extremity edema and weight gain of one month’s duration.
Read moreASH Clinical Research Training Institute Experience: Hematology and Oncology Fellows Network Discussion
ASH CRTI is a unique yearlong mentoring program for fellows and junior attendings at academic centers.
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