Hematopoiesis
For Trainees, By Trainees
Articles in Hematopoiesis are written for trainees by trainees, under the oversight of the ASH Trainee Council. The material published in Hematopoiesis is for informational purposes only. The opinions of the authors are their own and do not necessarily represent official policy of the American Society of Hematology. ASH does not recommend or endorse any specific tests, physicians, products, procedures, or opinions, and disclaims any representation, warranty, or guaranty as to the same. Reliance on any information provided in this publication is solely at your own risk.
Welcome from the Editor
Announcing Hematopoiesis, Our New ASH Trainee Council Newsletter by Trainees and for Trainees
Ajay Major, MD, MBA
Chair, ASH Trainee Council. Chief Fellow, University of Chicago, Chicago, IL (@majorajay)
The events of 2020 were unprecedented for all of us, disrupting the hematology trainee experience and the entire spectrum of medical education. For the ASH Trainee Council, creating online platforms for you, the hematologists-in-training that we represent, has become even more important as we all discovered the power of virtual spaces for learning and collaboration in the COVID era.
Contribute to Hematopoiesis: Submit your case study or research article to us!
Featured Content
A Case of Hematological Malignancy in Pregnancy: Therapeutic Complexities
Hina Khan, MD
Rabab Jafry
A 29-year-old woman (G3P2) at 6 weeks of gestation presented to the emergency department for vaginal bleeding over the preceding few days.
Management of Crystal Cryoglobulinemia in a Patient With Chronic Lymphocytic Leukemia
Ashley Dunton, MD
Shivi Jain, MD
A 64-year-old man with a history of heart failure with preserved ejection fraction and hypertension presented with progressive dyspnea.
Ureaplasma-induced Hyperammonemic Encephalopathy: An Acute Complication Post Haploidentical Allogenic Stem Cell Transplant
Rohail Badami
Michael Radford, MD
A 32-year-old woman with acute lymphoblastic lymphoma received a haploidentical allogeneic stem cell transplant (HSCT)
IgA Deficiency, Immune Globulin Treatment, and Pregnancy
David Daniel, MD
A Case of Melena in a Patient with Esophageal Adenocarcinoma: When Cytopenia Persists Despite Supportive Transfusions
Navya George, MD Maya Abdallah, MD
Rahul Ganatra, MD, MPH
A 73-year-old man with a medical history of stage III esophageal adenocarcinoma treated with neoadjuvant chemoradiotherapy, pulmonary embolism (PE) treated with a direct oral anticoagulant, and recent hospitalization for babesiosis presented with melena, persistent daily fevers, and hematuria.
Cardiotoxicity in Malignant Hematology: A Focus on CAR T-cell Therapy
Christina Snider, MD
Tanim Jain, MD
Treatment-related cardiotoxicity has been increasingly recognized as a challenge in the clinical management of cancer. Frequently used cancer drugs associated with a high risk of cardiotoxicity include anthracyclines, BCR-ABL kinase inhibitors, proteasome inhibitors, and Bruton tyrosine kinase inhibitors (BTKIs). Less is known about the potential acute and long-term cardiotoxic effects of chimeric antigen receptor T-cell (CAR-T) therapy, which has emerged as an efficacious treatment for hematologic malignancies.
Jak in the Brain: An Incidental Hematologic Malignancy Diagnosed From a Metastatic Lung Adenocarcinoma by Next Generation Sequencing
Eric Vick, MD, PhD
John Steffes, MD
Dr. Eric Vick (@Nodlike) and Dr. John Steffes describe the case of a man with long-standing mild leukocytosis found to have a brain mass, which was biopsied confirming metastatic recurrence of lung adenocarcinoma. Notably, molecular testing to the cerebral biopsy sample demonstrated a JAK2 mutation. The mutation was also found in a peripheral blood sample prompting further workup that led to the diagnosis of myelofibrosis.
#SHEmatologists: Recap of Women in Hematology Working Group at #ASH22 and What’s
Next
Rebecca Zon, MD
Xu Han, MD, PhD
Dr. Becky Zon and Dr. Xu Han highlights the ASH Women in Hematology Working Group activities at the ASH Annual Meeting and what is next on the horizon.
Superior Vena Cava Syndrome
Ricardo Ortiz, MD
A Thick Problem
Valentina Baez Sosa, MD
Kamille West-Mitchell, MD
James Kochenderfer, MD
Dr. Valentina Baez Sosa (@ValenBaezS), Dr. Kamille West-Mitchell (@Kwestmitchell), and Dr. James Kochenderfer describe the case of a 56-year-old man diagnosed with immunoglobulin A (IgA) kappa multiple myeloma who was treated with multiple chemotherapeutic regimens with a response and subsequent relapse.
Cardiac Considerations With Carfilzomib in a Patient Diagnosed With Multiple Myeloma
Aula Ramo, MD
Cortney McKay, MD
Vrushali Dabak, MD
Superior Vena Cava Syndrome
Ricardo Ortiz, MD
Adriana Malone, MD
Emergency Department Management of Sickle Cell Disease: A Point-of-Care Tool
Logan Ramsey, MD
Caroline Freiermuth, MD, MS, FACEP
Mentoring Matters: Perspectives From Basic Science Hematology Investigators
(Part 3)
Xu Han, MD, PhD
Moua Yang, MD, PhD
Dr. Xu Han (@PARty4Ever_) and Dr. Moua Yang (@MouaYang21) describe how a healthy mentor-mentee relationship is critical for academic and career success.
Mentoring Matters: Perspectives From Basic Science Hematology Investigators
(Part 2)
Xu Han, MD, PhD
Moua Yang, MD, PhD
Dr. Xu Han (@PARty4Ever_) and Dr. Moua Yang (@MouaYang21) describe how a healthy mentor-mentee relationship is critical for academic and career success.
Mentoring Matters: Perspectives From Basic Science Hematology Investigators
(Part 1)
Xu Han, MD, PhD
Moua Yang, MD, PhD
Dr. Xu Han (@PARty4Ever_) and Dr. Moua Yang (@MouaYang21) describe how a healthy mentor-mentee relationship is critical for academic and career success.
How Research as a Medical Student Shaped My Career Trajectory
Macy L. Early, MS4
Lydia H. Pecker, MD
Macy Early, MS4 (@macy_early), with her mentor Dr. Lydia Pecker (@LydiaPecker), reflects on the ways engaging in research shaped her career trajectory and aspirations throughout medical school, as she discovered a love for sickle cell disease and healthcare delivery sciences through research in reproductive health.
I’ve registered for ASH. Now what?
Ajay Major, MD, MBA
Rebecca Zon, MD