Jump to Main Content

ASH Clinical Practice Guidelines

ASH ISTH NHF WFH Clinical Practice Guidelines on von Willebrand Disease

The American Society of Hematology (ASH), in collaboration with the International Society on Thrombosis and Haemostasis (ISTH), National Hemophilia Foundation (NHF), and World Federation of Hemophilia (WFH), has developed clinical practice guidelines on the diagnosis and management of VWD.

Learn more about the development process behind the ASH ISTH NHF WFH VWD guidelines.

View the international survey which highlighted areas of importance to a diverse representation of stakeholders in the diagnosis and management of VWD, providing a framework for future guideline development and implementation.

VWD Guidelines: What You Should Know

These one-page snapshots provides a high-level summary of the ASH ISTH NHF WFH VWD guidelines. A snapshot of the full VWD guidelines is also available for download.

Guideline Implementation Tools and Resources

ASH Clinical Practice Guidelines App

The ASH Clinical Practice Guidelines App provides easy access to every recommendation from all guidelines published by ASH, including rationale for each recommendation, benefits and harms associated with each recommended course of action, and links to the complete evidence-to-decision tables used to develop the recommendations. This app is also available via web interface.

Download for iOS    Download for Android


This webinar highlights recommendations along with underlying evidence and rationale for the recommendations for the ASH ISTH NHF WFH guidelines on the diagnosis and management of von Willebrand disease.

Watch Webinar

Teaching Slides

Help your colleagues diagnose, manage, and treat VWD with the following teaching slides designed for easy dissemination:

Additional resources

The following resources, developed externally and based on the ASH ISTH NHF WFH VWD guidelines, are provided for reference. Please note that the American Society of Hematology does not endorse, nor is it responsible for, the content of these resources

user guide to Guidelines 

Learn how patients, clinicians, policymakers, researchers, and others may interpret and apply guideline information.

Learn more