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ASH Clinical Practice Guidelines on Venous Thromboembolism

New Guidelines
Click image for video of experts
discussing the new guidelines.

In 2014, in response to long-standing member interest, ASH initiated an effort to develop evidence-based clinical practice guidelines for hematology that meet the highest standards of development, rigor and trustworthiness. Development of these guidelines, including systematic evidence review, was supported by the McMaster University GRADE Centre, a world leader in guideline development. With their partnership, ASH brought together ten panels of more than 100 thrombosis experts to review evidence and formulate more than 200 recommendations on venous thromboembolism (VTE).

Learn more about the development process behind the VTE guidelines.

VTE Guideline Development

VTE Guideline

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Understanding Blood Clots

Understanding Blood Clots

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Signs of VTE

Signs of VTE

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Guideline Implementation Tools and Resources 

ASH guidelines are reviewed annually by expert work groups convened by ASH. Resources derived from guidelines that require updating are removed from the ASH website.

VTE Clinical Practice Guidelines Snapshot

VTE Guidelines: What You Should Know

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ASH Clinical Practice Guidelines App

The ASH Clinical Practice Guidelines App provides easy access to every recommendation from all guidelines published by ASH, including rationale for each recommendation, benefits and harms associated with each recommended course of action, and links to the complete evidence-to-decision tables used to develop the recommendations. This app is also available via web interface.

Download for iOS    Download for Android

ASH Pocket Guides App

The ASH Pocket Guides App includes all of ASH’s pocket guides, including the 2018 pocket guide on the Diagnosis and Management of Heparin-Induced Thrombocytopenia (HIT). In addition to the pocket guides, the app contains tools and calculators to aid in clinical decision making, including a 4Ts calculator (updated based on the 2018 guidelines). This app is also available via web interface.

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Pocket Guide

Printed versions of pocket guides are available for order on the ASH website, and at ASH meetings throughout the year. The following pocket guides are based on the ASH Clinical Practice Guidelines for Management of VTE:

Slide Sets

Help your colleagues diagnose, manage, and treat VTE with teaching slides designed for easy dissemination. Slide sets are available for the following ASH guidelines:


Listen to the podcasts below to learn more about ASH's VTE guidelines.

Patient Versions of the Guidelines

Adaptation of VTE Guidelines for Latin America

ASH partnered with 12 societies to adapt the ASH VTE Clinical Practice Guidelines for Latin America. The panel selected questions from the original ASH VTE guidelines that are clinically significant in Latin America and reviewed the evidence to form recommendations.

Available Guidelines

user guide to Guidelines 

Learn how patients, clinicians, policymakers, researchers, and others may interpret and apply guideline information.

Learn more