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ASH Clinical Practice Guidelines

ASH SCD Guidelines: Stem Cell Transplantation

In 2016, ASH initiated an effort to develop clinical practice guidelines on Sickle Cell Disease (SCD). These guidelines are part of a series of five guidelines ASH is developing on SCD to provide updated treatment guidelines that reflect the newest evidence about the disease, ensuring the medical community can better treat SCD and people with SCD can make the best decisions for their care.

Learn more about the development process behind the SCD guidelines.

Access the full guidelines on the Blood Advances website:

American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation

Guideline Implementation Tools and Resources

ASH guidelines are reviewed annually by expert work groups convened by ASH. Resources derived from guidelines that require updating are removed from the ASH website.

SCD Guidelines: What You Should Know

This one-page snapshot provides a high-level summary of the guidelines on transplantation for people with sickle cell disease.

ASH Clinical Practice Guidelines App

The ASH Clinical Practice Guidelines App provides easy access to every recommendation from all guidelines published by ASH, including rationale for each recommendation, benefits and harms associated with each recommended course of action, and links to the complete evidence-to-decision tables used to develop the recommendations. This app is also available via web interface.

Download for iOS    Download for Android

Pocket Guides

ASH has developed a series of brief, evidence-based pocket guides to help physicians provide quality care to patients. The pocket guides are available via the ASH Pocket Guides App for IOS and Android devices. This app is also available via web interface.

Download for iOS    Download for Android

Teaching Slides

Help your colleagues diagnose, manage, and treat SCD with teaching slides designed for easy dissemination.


Listen to the podcasts below to learn more about ASH's clinical guidelines