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ASH Clinical Practice Guidelines

ASH Clinical Practice Guidelines on Acute Myeloid Leukemia in Older Adults

The ASH Guidelines on Acute Myeloid Leukemia (AML) in Older Adults were published in 2020. These guidelines are intended to help older adults with AML and their healthcare providers make critical care decisions including if and how to proceed with cancer treatment and the need for blood transfusions for those in hospice care. In 2023, ASH will form a guideline panel to update the 2020 guidelines. A methodology team will conduct systematic reviews of new evidence, and the panel will revise previous recommendations.

Access the full guidelines on the Blood Advances website:

American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults

Learn more about the development process behind the AML guidelines. 

Guideline Implementation Tools and Resources

In 2022, ASH agreed to revise these guidelines. Derivative resources will be published with revised guidelines.

ASH Clinical Practice Guidelines App

The ASH Clinical Practice Guidelines App provides easy access to every recommendation from all guidelines published by ASH, including rationale for each recommendation, benefits and harms associated with each recommended course of action, and links to the complete evidence-to-decision tables used to develop the recommendations. This app is also available via web interface.

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ASH Pocket Guides App

The ASH Pocket Guides App includes all of ASH’s pocket guides. This app is also available via web interface.

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ASH Statements

ASH Statement in Support of Palliative Blood Transfusions in Hospice Settings

ASH Webinar

This webinar highlights recommendations along with underlying evidence and rationale for the recommendations for the ASH Guidelines for treating newly diagnosed acute myeloid leukemia in older adults.

Watch webinar