Hematologic Drug Shortage Information
Drug shortages are reaching an all-time high in the United States, especially in hematology care. ASH continues to keep members apprised of shortages as well as actively engage with Congress, federal agencies, including recent discussions with U.S. Food and Drug Administration (FDA), and other stakeholders to ensure continued access to safe and effective hematologic drugs. Please see below the recent hematologic shortages, the Society’s actions, and ways for members to get involved.
Cancer Drug Shortage Consensus Letter:
ASH, in partnership with organizations across the cancer community, developed a consensus statement identifying the primary drivers of the persistent drug shortages crisis in the United States and proposing actionable policy solutions to protect access to critical cancer medications.
The statement outlines three priorities that require immediate action to address:
Increasing transparency across the drug supply chain
Strengthening incentives for manufacturers to invest in high-quality, redundant supply system
Stabilizing the generic drug market
Recent Comments to Congress and the FDA
Current Hematologic Drug Shortages
- Amikacin Injection
- Aminocaproic Acid Injection, USP
- Anagrelide Hydrochloride Capsules
- Antropine Sulfate Injection
- Asparaginase Erwinia Chrysanthemi (Erwinaze)
- Azathioprine Tablet
- Calcium Gluconate Injection
- Cefazolin Injection
- Cefotetan Disodium Injection
- Cisplatin Injection
- Clindamycin Phosphate (Cleocin) Injection
- Deferoxamine Mesylate for Injection, USP
- Desmopressin Acetate Spray
- Dexamethasone Sodium Phosphate Injection
- Dexrazoxane Injection
- Dextrose 5% Injection Bags
- Diazepam Injection, USP
- Dimercaprol Injection
- Diphenhydramine Injection
- Doxorubicin (Adriamycin) Lyophilized Powder
- Etoposide Phosphate (Etopophos) Injection
- Heparin Sodium Injection
- Heparin Sodium and Sodium Chloride 0.9% Injection
- Hydrocortisone Sodium Succinate Injection, Powder, For Solution
- Leucovorin Calcium Lyophilized Powder for Injection
- Leuprolide Acetate Injection
- Lidocaine Hydrochloride (Xylocaine) Injection
- Lorazepam (Ativan) Injection
- Magnesium Sulfate Injection
- Methotrexate Sodium Injection
- Metronidazole Injection
- Morphine Sulfate (Astramorph PF, Duramorph, Infumorph) Injection (Preservative Free)
- Penicillin G Benzathine Injectable Suspension
- Piperacillin and Tazobactam (Zosyn) Injection
- Potassium Chloride Concentrate Injection
- Potassium Chloride Injection
- Potassium Phosphate Injection
- Prochlorperazine Injection
- Promethazine Injection
- Sodium Bicarbonate Injection
- Sodium Chloride 0.9% Injection Bags
- Sodium Phosphate Injection
- Thiotepa (Thioplex) for Injection
- Tobramycin Solution for Injection
- Vancomycin Hydrochloride for Injection
- Vinblastine Sulfate Injection
Discontinued Hematologic Drugs
- Aminocaproic Acid Solution
- Cytarabine Liposome (DepoCyt) Injection
- Cyancobalamin Injection
- Cyanocobalamin Spray
- Daprodustat Tablet
- Imatinib Mesylate Tablet
- Ibrutinib Tablet, Film Coated
- Imipenem and Cilastatin for Injection (Primaxin I.V. ADD-Vantage)
- Omacetaxine Mepesuccinate Injection, Powder, Lyophilized, For Solution
- PEGINTRON (peginterferon alfa-2b) REDIPEN
- Peritoneal Dialysis Solution
- Pralatrexate Solution
- Tranexamic Acid Tablet
- Voxelotor Tablet
Resolved Hematologic Drug Shortages
- Bleomycin Sulfate for Injection
- Cyanocobalamin (Vitamin B12) Injection
- Daunorubicin Hydrochloride Solution for Injection
- Famotidine Injection
- Heparin Sodium Injection
- Ondansetron (Zofran) Injection
- Protamine Sulfate Injection, Solution
- Ranitidine Hydrochloride (Zantac) Injection
- Rivaroxaban Granule, For Suspension
- Succimer Capsule
- Sulfamethoxazole and Trimethoprim (Bactrim) Oral Suspension
- Ticarcillin Disodium/Clavulanic Potassium (Timentin) Injection
Additional Resources
- For more information on drug shortages, visit the FDA drug shortage webpage.
- To report a drug shortage to FDA e-mail [email protected].
- To report concerns about drug price gouging due to shortages, contact FDA's Office of Criminal Investigations.
ASH's Comments to Congress and the U.S. Food and Drug Administration
- ASH SUBMITS COMMENTS TO CONGRESSIONAL LEADERS ON DRUG SHORTAGES
- ASH SUBMITS COMMENTS TO HOUSE ENERGY AND COMMERCE COMMITTEE ON THE STOP DRUG SHORTAGES ACT DISCUSSION DRAFT
- ASH Letter re: FDA Draft on Considerations for Externally Controlled Trials for Drug and Biological Products
- ASH Joins Coalition Letter Supporting Robust Discretionary Funding in FY 2024
- ASH Senate Appropriations FY 2023 Written Statement
- ASH Comments to FDA Draft on Considerations re: Accelerated Approval of Oncology Therapeutics
- ASH Letter on FDA Draft re: Capturing Post-Approval Efficacy Data on Cell and Gene Therapies
Media Coverage of Drug Shortages
- Read a New York Times article
- Listen to the Diane Rehm Show report on the issue
- Watch an ABC News report on this issue.
- Read a Los Angeles Times article
- Read a Wall Street Journal article
- Read a Washington Post article
- Read an Op-Ed in the Washington Post
For more information or to notify ASH of drug recalls or shortages, please contact ASH Policy and Practice Manager, Myra Masood at [email protected].