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ASH Agenda

Immunology and Immunotherapies

Understanding of basic immunology is essential to unlock the underpinnings of hematologic disease. Likewise, immunotherapy has revolutionized treatment for patients and is rapidly being applied to non-malignant disease to improve outcomes. Emphasis on both basic immunology and applications of immunotherapy is central to improved care in hematologic diseases as fundamentals of immunology, including B/T cell and thymus function, has broad applications to hematopoietic stem cell transplantation, transfusion medicine, cellular therapy, and novel immune based therapies.

  • Delineate how immune cell development and function influence hematopoietic stem cell development, transplantation, transfusion medicine, and cellular therapy
  • Identify biomarkers and mechanisms of disease risk, sensitivity and resistance, and novel combination therapies for blood diseases that incorporate immunotherapeutic modalities
  • Delineate the role of immune function and altered immune recognition in malignant and non-malignant hematologic diseases