Lymphoma Abstract Award Recipients

2018 Recipients

• Elena Battistello
  École Polytechnique Fédérale de Lausanne
  Lausanne, Switzerland
  Multimodal Inhibition of BCR Signaling in DLBCL Impacts DLBCL Evolution
• Joanne Dai
  Duke University
  Durham, NC
  Epstein-Barr Virus Latent Infection of B Cells Promotes Germinal Center-Like Apoptosis Resistance
• Franziska Gehringer
  Institute of Physiological Chemistry
  Ulm, Germany
  Tight Regulation of the PI3K-AKT-FOXO1 Axis Is Essential for Maintenance of the Dark Zone Program and Survival of Burkitt Lymphoma
• James Heward
  Barts Cancer Institute, Queen Mary University of London
  London, United Kingdom
  KDM5 Inhibition Is A Novel Therapeutic Strategy for the Treatment of KMT2D Mutant Lymphomas
• Kallesh Jayappa
  Beirne B. Carter Center for Immunology Research, University of Virginia
  Charlottesville, VA
  Diverse Microenvironmental Agonists Generate Drug Tolerant Persister Phenotype and Cancer Cell Proliferation in B Cell Malignancies
• Michael Jin
  Stanford University Medical Center
  Stanford, CA
  Circulating Tumor DNA as a Biomarker for the Noninvasive Genotyping and Monitoring of Classical Hodgkin Lymphoma
• Masaharu Kawashima
  Tokai University, Isehara-shi
  Kanagawa, Japan
  Upregulation of Immune Checkpoint Markers PDL1/2 on Monocytes Induced by Direct Contact With Hodgkin Cells
• Gero Knittel
  University Hospital Cologne
  Cologne, Germany
  MYD88 p.L265P and BCL2 Overexpression Cooperate in Lymphomagenesis in Mice
• Marvyn Koning
  Leiden University Medical Center
  Leiden, Netherlands
  Primary Cutaneous Follicle Center Lymphomas Express Heavily Mutated B-Cell Receptors With Acquired N-Glycosylation Motifs and Lack Ongoing Somatic Hypermutation
• Olga Kutovaya
  BC Cancer
  Vancouver, Canada
  UBR5 Mutations in Mantle Cell Lymphoma Lead to Increased Proliferation Through A Cyclin D1 Dependent Mechanism
• Marion Lacroix
  IRCM (Clinical Research Institute of Montreal)
  Montreal, Canada
  The Role of the RNA Helicase DDX3X in Human Burkitt Lymphoma
• Anna Lollies
  Institute of Cell Biology (Cancer Research)
  Essen, Germany
  Molecular Mechanisms in the Pathogenesis of Composite Lymphomas
• Kathryn Lurain
  National Cancer Institute, National Institutes of Health
  Washington, DC
  Radiation-Sparing Treatment of HIV-Related Primary Central Nervous System Lymphoma With Antiretroviral Therapy, Rituximab, and High-Dose Methotrexate
• Sayeef Mirza
  University of South Florida
  Tampa, FL
  Genomic Landscapes of CTCL and Sezary Syndrome
• Soumya Sundara Rajan
  University of Miami
  Miami, FL
  Genomic Editing of Transplantable Hematopoietic Stem Cells With CRISPR/Cas9 to Generate Npm1-Alk Through Chromosomal Translocation Accurately Models ALK+ T-Cell Lymphoma in Mice
• Ariel Sindel
  VCU Health System
  Richmond, VA
  Role of the PI3K Pathway in the Pathogenesis of Marginal Zone Lymphoma
• Vipul Shukla
  La Jolla Institute for Allergy and Immunology
  La Jolla, CA
  Tet Proteins Regulate Enhancer Function and Class Switch Recombination During B Cell Activation
• Ashima Shukla
  Sanford Burnham Prebys Medical Discovery Institute
  San Diego, CA
  Change in B Cell Receptor Isotype Alters the Tumor Forming Properties of Lymphoma B Cells
• Richard Sora
  Northwestern University Feinberg School of Medicine
  Glenview, IL
  Blocking Two Pathways of P27^Kip1Degradation Delays Tumor Onset in Mouse Model of Myc-driven Lymphoma
• Yasuhito Suehara
  University of Tsukuba
  Tsukuba, Japan
  Tp53 mutations Found in the Serum of Malignant Lymphoma Patients at Remission Derive From Clonal Hematopoiesis Rather Than Minimal Residual Disease
• Justin Taylor
  Memorial Sloan Kettering Cancer Center
  New York, NY
  Oncogenic Mutations in XPO1 Promote Lymphoid Transformation by Altering Nuclear-Cytoplasmic Localization of NFκB Signaling Intermediates
• Elena Viganò
  BC Cancer Research Centre
  Vancouver, Canada
  Recurrent IL4R Somatic Mutations in Diffuse Large B-Cell Lymphoma Lead to an Altered Gene Expression Profile and Changes in Tumor Microenvironment Composition
• Jillian Wise
  Oslo University Hospital, Institute for Cancer Research
  Westport , MA
  Relapsed/refractory Diffuse Large B-Cell Lymphomas Demonstrate Late Divergent Evolution and Increased TP53 Network Aberrations
• Julieta Sepulveda-Yanez
  Leiden University Medical Center
  Leiden, Netherlands
  Differential Mutational Pattern in Indolent B-Cell Lymphomas
• Tetsumi Yoshida
  Hiroshima University
  Hiroshima, Japan
  Patterns of IgH Rearrangement Can Predict Prognosis of Diffuse Large B-Cell Lymphoma in Association With CDC25A Overexpression

2016 Recipients

• Idit Sagiv-Barfi
  Stanford University
  Stanford, CA
  Which Checkpoint Antibody Combinations Are Synergistic?
• Emilia Bialopiotrowicz, PhD
  Institute of Hematology and Transfusion Medicine
  Warsaw, Poland
  Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B-Cell Lymphoma
• Rebecca Boddicker, PhD
  Mayo Clinic
  Rochester, MN
  Integrated Mate-Pair and RNA Sequencing Identifies Novel, Targetable Gene Fusions in Peripheral T-Cell Lymphoma
• Alexander Craig, MPhil
  Stanford University Medical Center
  Stanford, CA
  Methods of Circulating Tumor DNA Quantification in Plasma
• Ondrej Havranek, MD, PhD
  The University of Texas MD Anderson Cancer Center
  Houston, TX
  Features of Tonic B-Cell-Receptor Signaling in Diffuse Large B-Cell Lymphoma
• Keisuke Kataoka, MD, PhD
  Kyoto University
  Kyoto, Japan
  Novel Genetic Mechanism of Immune Evasion Involving PD-L1 in Aggressive Lymphomas
• Marvyn Koning, BSc
  Leiden University Medical Center
  Leiden, Netherlands
  Autonomous, Antigen-Independent B-Cell Receptor Signaling in Non-GCB DLBCL
• Robert Kridel
  BC Cancer Agency
  Vancouver, Canada
  Clonal Dynamics Shaping Histological Transformation and Progression in Follicular Lymphoma
• Olga Kutovaya, PhD
  BC Cancer Agency
  Vancouver, Canada
  The Role of UBR5 Mutations in the Pathogenesis of Mantle Cell Lymphoma
• Anja Mottok, MD
  BC Cancer Agency
  Vancouver, Canada
  Characterization of Genomic Rearrangements Involving CIITA and SOCS1 Using Targeted Capture Sequencing of Archival Tissue Specimens
• Samuel Ng, MD, PhD
  Dana-Farber Cancer Institute
  Boston, MA
  Exploring RhoA G17V-Mediated T-Cell Dysfunction
• Georgios Pongas, MD
  National Cancer Institute, National Institutes of Health
  Bethesda, MD
  Early Adaptive Responses of PI3K Activity Are Mediated Through PI3K-Alpha After PI3K-Delta Inhibition in ABC-DLBCL Cell Lines With MYD88 and CD79A or CD79B Mutations
• Julie Ross, PhD
  Institut de Recherches Cliniques de Montréal (IRCM)
  Montreal, Canada
  Loss of Functional Miz-1 Impairs c-Myc-Dependent B Cell Lymphomagenesis
• Florian Scherer, MD
  Stanford University Medical Center
  Stanford, CA
  Biopsy-Free Genotyping and Molecular Subtyping of Diffuse Large B-Cell Lymphoma
• Lili Wang, MD, PhD
  Harvard Medical School
  Boston, MA
  Integrated Dissection of Genetic and Transcriptional Heterogeneity in CLL by Single Cell Analysis

2014 Recipients

• Wendy Béguelin, PhD
  Weill Cornell Medical College
  New York City, NY
  EZH2 Cooperates With BCL6 to Induce Normal Germinal Center Reaction and Lymphomas Through Assembly of Non-Canonical PRC1 Complexes at Bivalent Chromatin Domains
• Mariano Cardenas, PhD
  Weill Medical College of Cornell University
  New York, NY
  Identification of Targetable Functional Groups on BCL6 Dimer Allows Rational Design of Potent and Selective Inhibitors With Activity in GCB- and ABC-Dlbcls
• Katerina Hatzi, PhD
  Weill Cornell Medical College
  New York, NY
  The Histone Demethylase LSD1 Acts as a BCL6 Corepressor in Germinal Center B Cells
• Ondrej Havranek
  The University of Texas MD Anderson Cancer Center
  Houston, TX
  The B-Cell Receptor Is Required for Optimal Viability, Growth, and Chemotherapy Resistance of Diffuse Large B-Cell Lymphoma Cell Lines of the Germinal Center B-Cell Subtype
• Chuanxin Huang, PhD
  Weill Cornell Medical College
  New York, NY
  The Bcl6 RD2 Domain Governs Commitment of Activated B-Cells to Form Germinal Centers
• Yanwen Jiang, PhD
  Weill Cornell Medical College
  New York, NY
  Deep-Sequencing Reveals Clonal Evolution Patterns and Mutation Events Associated With Relapse in B-Cell Lymphomas
• Melanie Märklin, MSc
  University of Tuebingen
  Tuebingen, Germany
  NFAT2 Is a Crucial Regulator of Anergy in CLL
• Jonathan Reichel
  Weill Cornell Medical College
  New York, NY
  Transcriptome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
• Florian Schere, MD
  University Medical Center Freiburg
  Freiburg, Germany
  Comprehensive Assessment of the Potential Role of B-Cell Receptor Antigen Recognition in the Pathogenesis of Follicular Lymphoma
• Sally Trabucco
  UMass Medical School
  Worcester, MA
  Inhibition of Bromodomain Proteins for the Treatment of Human Diffuse Large B-Cell Lymphoma
• Jiyuan Zhang, PhD
  Columbia University, Institute for Cancer Genetics
  New York, NY
  Inactivation of MLL2 Early During B Cell Differentiation Promotes Expansion of Mature Germinal Center B Cells: Implications for Lymphoma-Associated MLL2 Mutations