ASH Clinical Practice Guidelines on Acute Lymphoblastic Leukemia in Adolescents and Young Adults

In recent years, recognition of the complex and variable management of acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYAs), often drawing on both pediatric- and adult- inspired approaches, has highlighted the need for AYA-specific guidance.

ALL Guideline Topics

ALL AYA Frontline Management

These 2026 guidelines are for the frontline management of acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYAs).

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ALL AYA Relapsed Refractory

These 2026 guidelines are for the treatment of relapsed/refractory ALL in AYAs.

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