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Clinicians

ASH Clinical Practice Guidelines on Immune Thrombocytopenia

Over recent years, there has been an increase in available treatment options, evidence, and clinical experience related to the management of adults with primary immune thrombocytopenia (ITP). The 2026 ASH guidelines focus on initial and second-line therapy for adults with primary ITP and provide evidence-based recommendations to support treatment decision-making.

The 2019 ASH guidelines on ITP remain available on this page for recommendations on diagnosis, management, and other aspects of ITP care.

View the Full Guidelines

View the Full 2019 Guidelines

Download a Snapshot of the Guidelines


Guideline Implementation Tools and Resources

Visual Summary

This concise visual aid is intended to support understanding of the recommendations and to aid in clinical decision-making:

Teaching Slides

Educational slide sets to teach about ITP.

2026 slide set for initial and second-line therapy in adults with primary ITP

2019 slide set to help diagnose, manage, and treat ITP

Pocket Guides

The following pocket guides are based on the 2019 ASH Clinical Practice Guidelines for Immune Thrombocytopenia (ITP) and do not include recommendations from 2026:

Summary of 2026 Updates

Table describing key updates to the 2019 recommendations.

ITP Considering Initial Therapy

ITP Conversation Aid Banner

ASH has developed a shared decision-making tool to support clinicians and patients with immune thrombocytopenia (ITP) in considering initial medication choice.

Launch Tool

Podcasts

Listen to the Podcasts below to learn more about ASH's ITP guidelines.