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- Three Identical Strangers, One Pressing QuestionJune 12, 2019 | July-August 2019, Volume 16, Issue 4
Dr. Kristen O'Dwyer discusses "Three Identical Strangers," a documentary film about triplet boys born to a single mother and adopted by three separate families, who later learn of each other's existence after a chance encounter and discover they were unwitting participants in a research study.
- On the Road to a Better CAR: Identifying the Variables Associated With a Durable Response to CAR T-Cell Therapy in Relapsed/Refractory B-ALLJune 05, 2019 | July-August 2019, Volume 16, Issue 4
Dr. Fries and Dr. O'Dwyer discuss reported data on a cohort of adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia who received lymphodepleting chemotherapy followed by an infusion of autologous T cells, and look at variables associated with durable CAR-T therapy response.
- A Step Forward in the Treatment of Adolescent and Young Adult B-cell Acute Lymphoblastic LeukemiaApril 15, 2019 | May-June 2019, Volume 16, Issue 3
Dr. Boulware and Dr. O'Dwyer discuss a study that tested the efficacy and feasibility of a pediatric regimen for adolescent and young adult patients with newly diagnosed B- or T-lineage Philadelphia chromosome-negative acute lymphoblastic leukemia.
- Comprehensive Genomic Classification of Pediatric Mixed-Phenotype Acute LeukemiaFebruary 13, 2019 | March-April 2019, Volume 16, Issue 2
Dr. O'Dwyer and Dr. Becker review several reports that provide a comprehensive genomic analysis of pediatric mixed phenotype acute leukemia, comparing its "genomic landscape" to other pediatric acute leukemia subtypes.
Dr. O'Dwyer is Assistant Professor of Medicine in the Division of Hematology Oncology at the Wilmot Cancer Institute in the University of Rochester.