Lo L and Singer ST.

Thalassemia: current approach to an old disease.
Pediatr Clin N Am. 2002;49:1165-91.
Description: A review of the presentation, clinical effects and complications of thalassemias. PubMed citation number: 12580361

Olivieri NF and Brittenham GM.

Iron-chelating therapy and the treatment of thalassemia.
Blood. 1997; 89:739-61.
Description: Comprehensive review on the effects of iron overload and the clinical indications for chelation therapy.
PubMed citation number: 9028304

Rund D and Rachmilewitz E.

Pathophysiology of alpha- and beta-thalassemia: therapeutic implications.
Semin Hematol. 2001;38:343-9.
Description: A review of the consequences of globin chain synthesis imbalance with emphasis on membrane abnormalities and hypercoagulability.
PubMed citation number: 11605169

Weatherall DJ.

Pathophysiology of thalassemia.
Baillieres Clin Gaematol. 1998;11:127-46.
Description: Comprehensive review on the genetics and pathophysiology of both alpha and beta thalassemia.
PubMed citation number: 10872475

Wonke B.

Clinical management of ß-thalassemia major.
Semin Hematol. 2001;38:350-9.
Description: Concise clinical review on the clinical findings and management of beta thalassemia major.
PubMed citation number: 11605170

Return to Table of Contents