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3. Red Cell Aplasia and Hypoplasia

Red cell aplasia


Congenital

L.K. Diamond, K.D. Blackfan
Hypoplastic anemia
Am J Dis Child 56: 464 (1938)
Description: Diamond Blackfan anemia (DBA) was first recognized as a discrete entity in 1938 as a rare aregenerative anemia of childhood
PubMed citation number: N/A

B.P. Alter
Inherited bone marrow failure syndrome
Nathan and Oski’s Hematology of Infancy and Childhood, sixth edition, D.G. Nathan, S.H. Orkin, A.T. Look, D. Ginsburg, eds, W.B. Saunders Inc., Philadelphia, 2003, pp 280-365
Description: Up to date review of Diamond-Blackfan anemia
PubMed citation number: N/A

Acquired

I. Cherrick, G. Karayalcin, P. Lanzkowsky
Transient erythroblastopenia of childhood. Prospective study of fifty patients
Am J Pediatr Hematol Oncol 16: 320 (1994)
Description: Transient erythroblastopenia of childhood (TEC) is a form of acquired red cell aplasia. This article reports laboratory findings in TEC and a lack of physical abnormalities in patients with TEC
PubMed citation number: 7978049

B.P. Alter, N.S. Young
The bone marrow failure syndromes
Nathan and Oski’s Hematology of Infancy and Childhood, sixth edition, D.G. Nathan, S.H. Orkin, A.T. Look, D. Ginsburg, eds, W.B. Saunders Inc., Philadelphia, 2003
Description: Classic book providing an extensive review of pathogenesis, etiology, diagnosis and treatment of both congenital and acquired red cell aplasia
PubMed citation number: N/A

Red cell hypoplasia

Anemia of renal disease

J.W. Escgbach, J.C. Egrie, M.R. Downing, J.K. Browne, J.W. Adamson
Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial
N Engl J Med 316: 73-78 (1987)
Description: First paper documenting efficacy of recombinant erythropoietin to treat anemia in patients with renal failure
PubMed citation number: 3537801

T. Tarumoto, S. Imagawa, K. Ohmine, T. Nagai, M. Higuchi, N. Imai, N. Suzuki, M. Yamamoto, K. Ozawa
N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2
Blood 96: 1716-1722 (2000)
Description: Paper showing the molecular basis for erythropoietin suppression in patients with end-stage kidney disease
PubMed citation number: 10961869

N. Levin, G. Eknoyan, M. Pipp, E. Steinberg
National Kidney Foundation: dialysis outcome quality initiative – development of methodology for clinical practice guidelines
Nephrol Dial Transplant 12: 2060-2063 (1997)
Description: Clinical practice guidelines for dialysis patients including the recommended dosages of erythropoietin for patients with kidney disease
PubMed citation number: 9351065

Anemia of endocrine disorders

D.W. Golde, N. Bersch, I.J. Chopra, M.J. Cline
Thyroid hormones stimulate erythropoiesis in vitro
Br J Haematol 37: 173-177 (1977)
Description: Paper describing the role of thyroid hormones function on erythropoiesis
PubMed citation number: 603753

Zingraff, T. Drueke, P. Marie, N.K. Man, P. Jungers, P. Bordier J.
Anemia and secondary hyperparathyroidism
Arch Intern Med 138: 1650-1652 (1978)
Description: Paper describing the role of parathyroid hormone as an inhibitor of erythropoiesis
PubMed citation number: 718313

Anemia secondary to malnutrition and starvation

P. Amrein, R. Friedman, K. Kosinski, L. Ellman
Hematologic changes in anorexia nervosa
JAMA 241: 2190-2191 (1979)
Description: Review of hematologic changes in patients with a severe eating disorder
PubMed citation number: 219270

Iron deficiency anemia

F.H. Wians, J.E. Urban, J.H. Keffer, S.H. Kroft
Discriminating between iron deficiency anemia and anemia of chronic disease using traditional indices of iron status versus transferrin receptor concentration
Am J Clin Pathol 115: 112-118 (2001)
Description: Review of interpretation of indices of iron status and transferrin receptor concentration in the diagnosis of iron deficiency anemia and anemia of chronic disease
PubMed citation number: 11190796

W. Crosby
The rationale for treating iron deficiency anemia
Arch Intern Med 144: 471-472 (1984)
Description: Review of treatment of iron deficiency anemia
PubMed citation number: 6703813

Anemia secondary to marrow infiltration

W. Oster, F. Herrmann, H. Gamm, G. Zeile, A. Lindemann, G. Muller, T. Brune, H.P. Kraemer, R. Mertelsmann
Erythropoietin for the treatment of anemia of malignancy associated with neoplastic bone marrow infiltration
J Clin Oncol 8: 956-962 (1990)
Description: Description of the use of erythropoietin to treat anemia of bone marrow infiltration
PubMed citation number: 2189957

Other causes of hypoplastic anemia: Discussed in separate sections

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