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41. Mature T-cell Leukemia/Lymphomas

Peripheral T-cell lymphomas not otherwise specified

Lopez-Guillermo A, Cid J, Salar A, et al.

Peripheral T-cell lymphomas: initial features, natural history and prognostic factors in a seris of 174 patients diagnosed according to the R.E.A.L. classification.
Ann Oncol. 1998;9:849-55.
Description: Large case series of peripheral T-cell lymphomas. Provides data on frequency of different subtypes, prognosis and response to therapy.
PubMed citation number: 9789607

Ansell SM, Habermann TM, Kurtin PJ, et al.

Predictive capacity of of the International Prognostic Factor Index in patients with peripheral T-cell lymphoma.
J Clin Oncol. 1997;15:2296-301.
Description: Retrospective cases series. Demonstrates that the IPI is a powerful predictor of prognosis in patients with peripheral T-cell lymphoma.
PubMed citation number: 9196143

Gisselbrecht C, Gaulard P, Lepage E, et al.
Prognostic significance of T-cell phenotype in aggressive non-Hodgkin's lymphomas. Groupe d'Etudes des Lymphomes de l'Adulte (GELA).
Blood. 1998;92:76-82.
Description: Retrospective cohort study. Demonstrates than peripheral T cell lymphoma (anaplastic large cell subtype excepted) is a risk factor for poor outcome, independent of the international prognostic index.
PubMed citation number: : 9639502

Rudiger T, Weisenburger DD, Anderson JR, et al.
Peripheral T-cell lymphoma (excluding anaplastic large-cell lymphoma): results from the Non-Hodgkin's Lymphoma Classification Project.
Ann Oncol. 2002;13:140-9.
Description: Case series of all of the peripheral T-cell lymphomas (n=96) diagnosed within the international lymphoma classification project. Provides epidemiologic, clinical and prognostic data on this rare type of lymphoma.
PubMed citation number: 11863096

Anaplastic large-cell lymphoma

Weisenburger DD, Anderson JR, Diebold J, et al.

Systemic anaplastic large-cell lymphoma: results from the non-Hodgkin's lymphoma classification project.
Am J Hematol. 2001;67:172-8.
Description: Case series of all of the anaplastic large cell lymphomas (n=33) diagnosed within the international lymphoma classification project. Provides epidemiologic, clinical and prognostic data on this rare type of lymphoma.
PubMed citation number: 11391714

Drexler HG, Gignac SM, von Wasielewski R, et al.

Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas.
Leukemia. 2000;14:1533-59.
Description: Review of the pathobiology of the t(2;5) translocation and it’s clinical significance in anaplastic large cell and other lymphomas.
PubMed citation number: 10994999

AILD

Sallah S, Gagnon GA.

Angioimmunoblastic lymphadenopathy with dysproteinemia: emphasis on pathogenesis and treatment.
Acta Haematol. 1998;99:57-64.
Description: Review of the pathogenesis, clinical presentation, complications, and management of AILD.
PubMed citation number: 9554450

Hepatosplenic gamma delta T-cell lymphoma

Belhadj K, Reyes F, Farcet JP, et al.

Hepatosplenic gamma delta T-cell lymphoma is a rare clinicopathologic entity with poor outcome: report on a series of 21 patients.
Blood. 2003;102:4261-4269.
Description: Recent case series of 21 patients with hepatosplenic gamma-delta T cell lymphoma. Provides information on the clinical history, immunophenotype and cytogenetics of the patients.
PubMed citation number: 12907441

ATLL
Shimoyama M and members of the lymphoma study group (1984-87).

Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma.
Br J Haematol. 1991;79:428-37.
Description: Proposes diagnostic criteria for 4 clinical subtypes of ATLL. Demonstrates that in a retrospective case series of 818 patients the proposed diagnostic criteria separated the patients into statistically distinct survival curves.
PubMed citation number: 1751370

Mortreux F, Gabet AS, Wattel E.

Molecular and cellular aspects of HTLV-1 associated leukemogenesis in vivo.
Leukemia. 2003;17:26-38.
Description: Review of the critical role of HTLV in the pathogenesis of ATLL.
PubMed citation number: 12529656

Pawson R, Mufti GJ, Pagliuca A.

Management of Adult T-cell Leukaemia/Lymphoma.
Br J Haematol. 1998;100:453-8.
Description: Succinct review of the presentation and management of ATLL.
PubMed citation number: 9504625

Gill PS, Harrington W, Kaplan MH, et al.

Treatment of adult T-cell leukemia-lymphoma with a combination of interferon alfa and zidovudine.
N Engl J Med. 1995;332:1744-8.
Description: Prospective single-arm study of 19 patients with either acute or lymphomatous form of ATLL treated with zidovudine and interferon. Demonstrated activity of this combination against ATLL.
PubMed citation number: 7760890

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