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31. Lymphoplasmacytic lymphoma, Waldenstrom’s Macroglobulinemia, and Castleman’s Disease

Lymphoplasmacytic lymphoma/Waldenstrom’s macroglobulinemia

Gobbi, P. G., Bettini, R., Montecucco, C., Cavanna, L., Morandi, S., Pieresca, C., Merlini, G., Bertoloni, D., Grignani, G. and Pozzetti, U.

(1994). Study of prognosis in Waldenstrom's macroglobulinemia: a proposal for a simple binary classification with clinical and investigational utility.
Blood 83(10): 2939-45.
Description: The investigators find that among many variables studied, only hemoglobin, age, weight loss, and cryoglobulinemia independently affected survival in patients with Waldenstrom’s macroglobulinemia.
PubMed citation number: 8180389

Mazzaro, C., Franzin, F., Tulissi, P., Pussini, E., Crovatto, M., Carniello, G. S., Efremov, D. G., Burrone, O., Santini, G. and Pozzato, G.

(1996). Regression of monoclonal B-cell expansion in patients affected by mixed cryoglobulinemia responsive to alpha-interferon therapy.
Cancer 77(12): 2604-13.
Description: Type II mixed cryoglobulinemia is associated with a high prevalence of bone marrow B-cell lymphomas. IFN-alpha appears to be an effective treatment and can induce regression of the lymphoproliferative disorder.
PubMed citation number: 8640712

Iida, S., Rao, P. H., Ueda, R., Chaganti, R. S. and Dalla-Favera, R.

(1999). Chromosomal rearrangement of the PAX-5 locus in lymphoplasmacytic lymphoma with t(9;14)(p13;q32).
Leuk Lymphoma 34(1-2): 25-33.
Description: The t(9;14)(p13;q32) chromosomal translocation is associated with lymphoplasmacytic lymphoma (LPL). It juxtaposes the PAX-5 gene encoding a transcription factor - BSAP: B-cell specific activator protein - to the Ig heavy chain gene (IgH) locus.
PubMed citation number: 10350329

Dhodapkar, M. V., Jacobson, J. L., Gertz, M. A., Rivkin, S. E., Roodman, G. D., Tuscano, J. M., Shurafa, M., Kyle, R. A., Crowley, J. J. and Barlogie, B.

(2001). Prognostic factors and response to fludarabine therapy in patients with Waldenstrom macroglobulinemia: results of United States intergroup trial (Southwest Oncology Group S9003).
Blood 98(1): 41-8.
Description: The first prospective observational multicenter clinical trial of WM. Treatment was fludarabine; ORR was 36%. The authors also developed a staging system.
PubMed citation number: 11418461

Wulf, G. and S. Pool

(2001). Images in clinical medicine. Waldenstrom's macroglobulinemia.
N Engl J Med 344(11): 816.
PubMed citation number: 11248158

Reviews

Dimopoulos, M. A. and R. Alexanian

(1994). Waldenstrom's macroglobulinemia.
Blood 83(6): 1452-9.
PubMed citation number: 8123836

Dimopoulos MA, Panayiotidis P, Moulopoulos LA, Sfikakis P, Dalakas M.

Waldenstrom’s macroglobulinemia: clinical features, complications, and management.
J Clin Onc 2000;18(1):214-26.
Description: A review article of Waldenstom’s Macroglobulinemia
PubMed citation number:10623712

Pangalis, G. A., Angelopoulou, M. K., Vassilakopoulos, T. P., Siakantaris, M. P. and Kittas, C.

(1999). B-chronic lymphocytic leukemia, small lymphocytic lymphoma, and lymphoplasmacytic lymphoma, including Waldenstrom's macroglobulinemia: a clinical, morphologic, and biologic spectrum of similar disorders.
Semin Hematol 36(2): 104-14.
PubMed citation number: 10319379

Tallman, M. S. and D. Hakimian

(1995). Purine nucleoside analogs: emerging roles in indolent lymphoproliferative disorders.
Blood 86(7): 2463-74.
PubMed citation number: 7670093

Castleman’s disease

Castleman, B., L. Iverson and Menendez, V. P.

(1956). Localized mediastinal lymph node hyperplasia resembling thymoma.
Cancer 9(4): 822-30.
Description: The original description.
PubMed citation number: 13356266

Sickel, J. Z.

(1995). Images in clinical medicine. Castleman's disease.
N Engl J Med 333(12): 776.
PubMed citation number: 7643885

Dupin, N., Gorin, I., Deleuze, J., Agut, H., Huraux, J. M. and Escande, J. P.

(1995). Herpes-like DNA sequences, AIDS-related tumors, and Castleman's disease.
N Engl J Med 333(12): 798.
PubMed citation number: 7643891

Belec, L., Mohamed, A. S., Authier, F. J., Hallouin, M. C., Soe, A. M., Cotigny, S., Gaulard, P. and Gherardi, R. K.
(1999). Human herpesvirus 8 infection in patients with POEMS syndrome-associated multicentric Castleman's disease.
Blood 93(11): 3643-53.
Description: Multicentric Castleman’s disease is associated with the POEMS syndrome. Seven of 13 (54%) POEMS patients had HHV-8 detectable, and the majority was detected in the subset of POEMS patients with MCD.
PubMed citation number: 10339470

Corbellino, M., Bestetti, G., Scalamogna, C., Calattini, S., Galazzi, M., Meroni, L., Manganaro, D., Fasan, M., Moroni, M., Galli, M. and Parravicini, C.

(2001). Long-term remission of Kaposi sarcoma-associated herpesvirus-related multicentric Castleman disease with anti-CD20 monoclonal antibody therapy.
Blood 98(12): 3473-5.
PubMed citation number: 11719390

Review

Bowne, W. B., Lewis, J. J., Filippa, D. A., Niesvizky, R., Brooks, A. D., Burt, M. E. and Brennan, M. F.

(1999). The management of unicentric and multicentric Castleman's disease: a report of 16 cases and a review of the literature.
Cancer 85(3): 706-17.
PubMed citation number: 10091744

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