Autoimmune Hemolytic Anemia
Pathophysiology
Fludarabine-related autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia.
Myint H, Copplestone JA, Orchard J, et al.
Br J Haematol. 1995;91:341-344.
Description : This paper is one of the first descriptions of autoimmune hemolytic anemia in patients with chronic lymphocytic leukemia (CLL) treated with fludarabine and potential mechanisms of causality.
PubMed citation number: 8547072
Mechanisms of immunological tolerance loss versus erythrocyte self-antigens and autoimmune hemolytic anemia.
Fagiolo E, Toriani-Terenzi C.
Autoimmunity. 2003;36:199-204.
Description: This paper reviews potential mechanisms of autoimmune hemolytic anemia on a cellular level. PubMed citation number: 14563012
Drug-induced hemolytic anemias: increasing complications to therapeutic interventions.
Wright MS.
Clin Lab Science. 1999;12:115-118.
Description: This paper discusses severe drug-induced immune hemolysis caused by several different classes of drugs.
PubMed citation number: 10387489
NIH conference: pathophysiology of immune hemolytic anemia.
Ann Inter Med. 1977;87:210-222.
Description: This paper reviews what is known regarding the pathogenesis of autoimmune hemolytic anemia from a cellular level.
PubMed citation number: 329729
Diagnosis
A new test for the detection of weak and “incomplete” Rh agglutinins.
Coombs RRA, Mourant AE, Rrace RR.
Br J Exp Path. 1945;26:255-266.
Description : This is the original paper describing the methodology and purpose of the Coombs test.
PubMed citation number: N/A
The predictive value of serum haptoglobin in hemolytic disease.
Marchand A, Galen RS, Van Lente F.
JAMA. 1980;243:1909-1911.
Description: This paper describes the sensitivity and specificity of using serum haptoglobin in predicting hemolytic disease.
PubMed citation number: 7365971
Treatment
Rituximab for the treatment of refractory autoimmune hemolytic anemia in children.
Zecca M, Nobili B,Ramenghi U,et al.
Blood. 2003;101:3857-3861.
Description: This paper describes the course of 15 pediatric patients with refractory autoimmune hemolytic anemia treated with rituximab.
PubMed citation number: 12531800
Mycophenolate mofetil for the treatment of refractory auto-immune haemolytic anaemia and auto-immune thrombocytopenia purpura.
Howard J, Hoffbrand AV, Prentice HG, Mehta A.
Br J Haematol. 2002;117:712-715.
Description: This paper describes the use of the immunosuppressive agent mycophenolate mofetil in patients with autoimmune hemolytic anemia refractory to first-line management.
PubMed citation number: 12028047
Review
The acute and transient nature of idiopathic immune hemolytic anemia in childhood.
Buchanan GR, Boxer LA, Nathan DG.
J Pediatr. 1976;88:780-783.
Description : This is one of the few reviews that describes the pattern of autoimmune hemolytic anemia in the pediatric population.
PubMed citation number: 1271139
Autoimmune hemolytic anemia.
Gehrs BC , Friedberg RC.
Am J Hematol. 2002;69:258-271.
Description: This is a comprehensive review of the classifications of AIHA, and the respective causal antibodies, demographics, etiology, clinical presentation, laboratory evaluation, and treatment options.
PubMed citation number: 11921020
Immune haemolytic disease: the autoimmune haemolytic anaemias.
Pirofsky B.
Clin Haematol. 1975;4:167.
Description : This is one of the first reviews to describe the complexity of diagnosis and mechanisms of hemolytic anemia. It provided an algorithm for steroid treatment and second-line therapies that is often still used today. PubMed citation number: 1102181
The variability of hemolysis in the cold agglutinin syndrome.
Rosse WF, Adams JP.
Blood. 1980;56:409-416.
Description: This paper reviews the course of patients with cold agglutinin syndrome.
PubMed citation number: 7407408
Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features.
Mauro FR, Foa R, Cerretti R, et al.
Blood. 2000;95:2786-2792.
Description: This is a comprehensive review of autoimmune hemolytic anemia in patients with chronic lymphocytic leukemia.
PubMed citation number: 10779422