The T-cell Skin Lymphomas
(mycoses fungoides, Sezary syndrome, and cutaneous T-cell lymphoma)
Diagnosis
Report of the committee on staging and classification of cutaneous T-cell lymphomas.
Bunn PA, Lamberg SI.
Cancer Treat Rep. 1979;63:275-278.
Description: Original staging system for mycosis fungoides/Sezary syndromes.
PubMed citation number: 445521
Histopathologic staging at initial diagnosis of mycosis fungoides and the Sezary syndrome. Definition of three distinctive prognostic groups.
Sausville EA, Eddy JL, Makuch RW, et al.
Ann Intern Med. 1988;109:372-382.
Description: Simplified staging system for mycosis fungoides/Sezary syndrome.
PubMed citation number: 3408055
EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer.
Willemze R, Kerl H, Sterry W, et al.
Blood. 1997;90:354-731.
Description: A classification system for cutaneous lymphoma that attempts to capture the distinct clinical and pathologic features of the cutaneous lymphomas.
PubMed citation number: 9207472
Treatment
A randomized trial comparing combination electron-beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides.
Kaye FJ, Bunn PA Jr, Steinber SM, et al.
N Engl J Med. 1989;321:1784-1790.
Description: Randomized controlled trial of combined therapy (electron beam + chemo) versus topical treatment. Reports high toxicity but no improvements in disease-free or overall survival with combined modality therapy.
PubMed citation number: 2594037
Systemic therapy of cutaneous T-cell lymphomas (mycosis fungoides and the Sezary syndrome).
Bunn PA Jr, Hoffman SJ, Norris D, et al.
Ann Intern Med. 1994;121:592-602.
Description: Systematic review of the use of systemic therapy for mycosis fungoides and Sezary syndrome. Concludes that systemic therapy is active, but not curative.
PubMed citation number: 8085692
Interferon in the treatment of cutaneous T-cell lymphoma.
Olsen EA, Bunn PA Jr.
Hematol Oncol Clin North Am. 1995;9:1089-1107.
Description: Review of the use of interferon in the treatment of mycosis fungoides and Sezary syndrome.
PubMed citation number: 8522486
Topical corticosteroids for mycosis fungoides. Experience in 79 patients.
Zackheim HS, Kashani-Sabet M, Amin S.
Arch Dermatol. 1998;134:949-954.
Description: Largest reported case series of clinical experience with steroids for MF.
PubMed citation number: 9722724
Phototherapy for cutaneous T-cell lymphoma.
Baron ED, Stevens SR.
Dermatol Ther. 2003;16:303-310.
Description: A review of the different types of phototherapy available (broadband UVB, PUVA, etc), and their role in the management of cutaneous T-cell lymphoma.
PubMed citation number: 14686973
Prognosis
Twenty-year trends in the reported incidence of mycosis fungoides and associated mortality.
Weinstock MA, Gardstein B.
Am J Public Health. 1999;89:1240-1244.
Description: Epidemiologic data on incidence and prognosis of MF.
PubMed citation number: 10432915
Extracorporeal photochemotherapy alone or with adjuvant therapy in the treatment of cutaneous T-cell lymphoma: a 9-year retrospective study at a single institution.
Bisaccia E, Gozalez J, Palangio M, et al.
J Am Acad Dermatol. 2000;43:263-271.
Description: Retrospective case series of photochemotherapy for cutaneous T-cell lymphoma. Reports complete response rate of 14% and partial response rate of 41%.
PubMed citation number: 10906649
Total skin electron radiation in the management of mycosis fungoides: consensus of the European Organization for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Project Group.
Jones GW, Kacinski BM, Wilson LD, et al.
J Am Acad Dermatol. 2002;47:364-370.
Description: Consensus statement from the EORTC Cutaneous Lymphoma Project Group on the role of total skin electron radiation in the treatment of mycosis fungoides.
PubMed citation number: 12196745
Review
Lymphoma of the skin.
Connors JM, His ED, Foss FM.
Hematology (Am Soc Hematol Educ Program). 2002:263-82.
Description: Succinct review.
PubMed citation number: 12446427