Follicular lymphoma
Pathophysiology
Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation.
Ngan BY, Chen-Levy Z, Weiss LM, Warnke RA, Cleary ML.
N Engl J Med. 1988;318:1638-1644.
Description: This is one of the first papers that described the association of the bcl-2 proto-oncogene and its expression in virtually all studied follicular lymphomas.
PubMed citation number: 3287162
The natural history of initially untreated low-grade non-Hodgkin's lymphomas.
Horning SJ, Rosenberg SA.
N Engl J Med. 1984;311:1471-1475.
Description: This paper reports on the natural history of untreated low-grade NHL including follicular lymphomas and provides an early basis for observation as a treatment.
PubMed citation number: 6548796
Treatment
Is radiotherapy curative for stage I and II low-grade follicular lymphoma? results of a long-term follow-up study of patients treated at Stanford University.
Mac Manus MP, Hoppe RT.
J Clin Oncol. 1996;14:1282-1290.
Description: This is a retrospective review describing outcomes of patients with stage I and II follicular lymphomas treated with radiation alone.
PubMed citation number: 8648385
Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy.
Czuczman MS, Grillo-Lopez AJ, White CA, et al.
J Clin Oncol. 1999;17:268-276.
Description: This is the first report demonstrating the safety and efficacy of rituximab in combination with standard-dose systemic chemotherapy in the treatment of indolent B-cell lymphoma (including follicular lymphoma).
PubMed citation number: 10458242
Pivotal study of iodine I 131 tositumomab for chemotherapy-refractory low-grade or transformed low-grade B-cell non-Hodgkin's lymphomas.
Kaminski MS, Zelenetz AD, Press OW, et al.
J Clin Oncol. 2001;19:3918-3928.
Description: This study demonstrates the effectiveness of radioimmunotherapy in patients with chemotherapy-refractory low-grade lymphoma.
PubMed citation number: 11579112
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.
McLaughlin P, Grillo-Lopez AJ, Link BK, et al.
J Clin Oncol. 1998;16:2825-2833.
Description: This study describes the efficacy of a commonly used regimen of single-agent rituximab for relapsed indolent lymphoma.
PubMed citation number: 9704735
Comparison of autologous and allogeneic hematopoietic stem cell transplantation for follicular lymphoma.
van Besien K, Loberiza FR Jr, Bajorunaite R, et al.
Blood 2003;102:3521-3529.
Description: This is a retrospective evaluation comparing the outcomes of patients undergoiong autologous and allogeneic stem cell transplantation for follicular lymphoma, revealing similar 5-year overall survival rates. Increased transplantation-related mortality was seen with allogeneic transplant recipients, with increased recurrences with autologous transplant recipients.
PubMed citation number: 12893748
Review
Clinicopathologic analysis of follicular lymphoma occurring in children.
Lorsbach RB, Shay-Seymore D, Moore J, et al.
Blood. 2002;99:1959-1964.
Description: This paper describes the clinical and histological features and outcomes of 23 patients with follicular lymphoma carrying this rare pediatric diagnosis.
PubMed citation number: 11877266
Intensive therapies in follicular non-Hodgkin lymphomas.
Hunault-Berger M, Ifrah N, Solal-Celigny P.
Blood. 2002;100:1141-1152.
Description: This paper reviews studies involving stem cell transplantation in treating follicular lymphomas. PubMed citation number: 12149190
Follicular lymphomas: a review of treatment modalities.
Soubeyran P, Debled M, Tchen N, et al.
Crit Rev Oncol Hematol. 2000;35:13-32.
Description: This is a comprehensive review of a large body of literature on each of the treatment modalities used in caring for patients with follicular lymphoma.
PubMed citation number: 10863149