Lymphocytosis - Bernard Greenberg, MD
University of Connecticut Health Center, Farmington, CT

Copyright of the American Society of Hematology, 2006. ISSN: 1931-6860.

VI. PROGNOSIS/CLINICAL COURSE

Proceed to Staging: There are 2 staging systems in general use for CLL. Using the Rai classification system, what is the patient's present stage?

Rai

Rai Classification
Stage	Description	Median Survival (Years)
O	lymphocytosis > 5,000/mL Bone marrow infiltration >40%	>12
I	As in O, plus adenopathy	10
II	As in O or I, plus splenomegaly and/or hepatomegaly	8
III	As in O, I or II, plus anemia (Hb < 11gm%)	2
IV	As in O, I, II or III, plus thrombocytopenia (platelets < 100,000/µL)	2

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