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Teaching Cases

Anemia and Jaundice in a Newborn – Charles T. Quinn, MD
UT Southwestern Medical Center, Dallas, TX

Copyright of the American Society of Hematology, 2006. ISSN: 1931-6860.


I. HistoryII. Physical ExamIII. Laboratory DataIV. Differential Diagnosis
V. PathophysiologyVI. Prognosis/Clinical CourseVII. Teaching PointsVIII. Bibliography

V. PATHOPHYSIOLOGY

In light of the laboratory data you have obtained so far, what is the next step you should take to make a definitive diagnosis?

Test whether the father is HPA-1a (PLA1) positive
Determine the antigenic specificity of the antibody
Perform extended RBC antigen typing on the mother and child
Determine the HLA type of the mother and child


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