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Teaching Cases

GI Bleeding – David Green, MD, PhD
Northwestern University, Feinberg School of Medicine, Chicago, IL

Copyright of the American Society of Hematology, 2006. ISSN: 1931-6860.


I. HistoryII. Physical ExamIII. Laboratory DataIV. Differential Diagnosis
V. PathophysiologyVI. Prognosis/Clinical CourseVII. Teaching PointsVIII. Bibliography

IV. DIFFERENTIAL DIAGNOSIS

This patient has a normal platelet count with a prolonged bleeding time, a normal PT, and a prolonged aPTT. Which of the following disorders is most likely?

Heparin Therapy
Low factor VIII due to hemophilia A
Low factor IX due to hemophilia B
Low factor XI
Low factor XII, Low prekallikrein (PK) or high molecular weight kininogen (HMWK)
Lupus Anticoagulant
Von Willebrand’s disease

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