May-June 2018, Volume 15, Issue 3
A Real Nose-Pincher
Published on: April 23, 2018
A 68-year-old man with a history of polycystic kidney disease presented five months postcadaveric renal transplantation with new-onset neutropenia and anemia, as well as a rising creatinine (2.59 mg/dL the prior week) with no other significant symptoms. A concurrent complete blood count showed the following:
White blood cell count 2.25 K/μL (absolute neutrophil count 0.71 K/μL)
Hemoglobin 7.9 g/dL
Mean corpuscular volume 86.2 fL
Platelet count 160 K/μL.
A 95-gene next-generation sequencing myeloid panel identified no pathogenic variants or copy number alterations. Metaphase cytogenetics revealed a normal karyotype. Two images from the peripheral blood smear and one image of the bone marrow biopsy are shown in Figures 1 and 2.
back to top