- A New Therapy for Sickle Cell Disease: FDA Approves Oral L-glutamine for Prevention of Acute Vaso-occlusive Events in Children and AdultsOctober 02, 2018 | November-December 2018, Volume 15, Issue 6
Dr. DeBaun discusses the study that led to FDA approval of oral L-glutamine for the prevention of acute vaso-occlusive events in children and adults with sickle cell disease.
- A New Strategy for the Prevention of Adverse Maternal and Fetal Outcomes in Pregnant Women With Sickle Cell Disease: The Oxygen Therapy and Pregnancy in SCD Trial (DR02G)September 10, 2018 | September-October 2018, Volume 15, Issue 5
Dr. DeBaun reviews a study that looks at outcomes for pregnant women with sickle cell disease who are randomly assigned to home-based oxygen therapy versus no home-based oxygen therapy.
- Another Sickle Cell Trait Myth Bites the Dust: Sickle Cell Trait Is Not Associated With Ischemic StrokeJuly 16, 2018 | July-August 2018, Volume 15, Issue 4
Dr. DeBaun discusses a study that presents strong evidence that sickle cell trait is not associated with ischemic stroke.
- Professionalism and the Written Word: Attitudes and Words Matter in Medical Care for Adults With SCDApril 04, 2018 | May-June 2018, Volume 15, Issue 3
Dr. DeBaun highlights the importance of our words and actions when dealing with adult patients with sickle cell disease and the need to correct written and oral language that stigmatizes patients with vaso-occlusive pain.
- What We Know and Do Not Know About Chronic Pain in Adults With Sickle Cell DiseaseFebruary 02, 2018 | March-April 2018, Volume 15, Issue 2
Dr. DeBaun discusses available information regarding the most common problem affecting 50 percent of adults with sickle cell disease, recurrent chronic pain.
- The Year's Best in Sickle Cell Disease for 2017January 09, 2018 | January-February 2018, Volume 15, Issue 1
Dr. DeBaun discusses the successful completion of the phase II trial (largest completed randomized controlled trial in SCD) using the anti-P-selectin antibody crizanlizumab for the prevention of acute vaso-occlusive pain events in SCD and two other important discoveries in 2017 for treating SCD.
- Yet Another Complication of Sickle Cell Disease: High Incidence of Venous Thromboembolism and Its Association With Earlier DeathOctober 10, 2017 | November-December 2017, Volume 14, Issue 6
Dr. DeBaun reviews the risk of venous thromboembolism for children and adults with sickle cell disease.
- Another Myth About Sickle Cell Trait Bites the DustAugust 14, 2017 | September-October 2017, Volume 14, Issue 5
Dr. DeBaun reviews studies that bust the myth that sickle cell trait is associated with common medical morbidities.
- Cautiously Optimistic About Gene Therapy in Sickle Cell Disease: A New Arrow in the Quiver for CureJuly 01, 2017 | July-August 2017, Volume 14, Issue 4
Dr. DeBaun sheds light on how gene therapy provides a new option for curing sickle cell disease, a disease which, so far, only has one FDA-approved disease-modifying agent.
- Another Therapeutic Agent in the Pipeline for Preventing Acute Vaso-Occlusive Events in Sickle Cell DiseaseMay 01, 2017 | May-June 2017, Volume 14, Issue 3
Dr. DeBaun looks at experiments using ARQ 092 as a possible therapeutic agent for preventing acute vaso-occlusive events in sickle cell disease.