Attack of the Clones: CHIP in the Clinic
In this No Data Zone piece, Drs. Rafael Bejar and Mikkael Sekeres discuss CHIP in aging patients, with next steps for real-world treatment strategies.
A New Standard of Care for Children and Young Adults With T-cell Acute Lymphoblastic Leukemia
Dr. Teachey reviews a study that shows outstanding outcomes for children and young adults with T-cell acute lymphoblastic leukemia that have raised the bar and established
Dr. Raje and Dr. Yee look at the RVD regimen (lenalidomide, bortezomib, and dexamethasone) as standard of care in newly diagnosed multiple myeloma.
Dr. Raje and Dr. Yee cover efforts to identify new pathways to treat multiple myeloma relapse.
Dr. Raje and Dr. Yee covers the DETERMINATION trial, which will provide greater clarity on how long to use maintenance lenalidomide and whether longer maintenance will narrow the gap in PFS between upfront and deferred transplant approaches.
Drs. Raje, Yee, and Lohr discuss the development of a new tool for exploring the complexity of multiple myeloma through circulating myeloma cells, which could replace bone marrow biopsies and permits analysis to be performed at multiple time points.
Dr. Raje, Dr. Yee and Dr. O'Donnell discuss various daratumumab combinations that have emerged as options for the treatment of multiple myeloma.
Dr. Raje and Dr. Yee discuss a study that looks at the use of pembrolizumab in combination with lenalidomide or pomalidomide to treat multiple myeloma as a form of checkpoint inhibition, a new important tool in cancer treatment.
Drs. Raje, O'Donnell, and Yee discuss progress in drugs for the treatment of multiple myeloma, especially immuno-oncology and monoclonal antibodies (MoABs).
Drs. Raje and Yee discuss two trials with elotuzumab and daratumumab that use monoclonal antibodies in the treatment of multiple myeloma.
Dr. Raje and Dr. Yee discuss the need for new agents in the therapy or treatment of patients with multiple myeloma, taking into account the FDA approval of penobinostat, and a study that looks at HDAC inhibition.
Dr. Yee and Dr. Raje review several trials to explain new courses of treatment for multiple myeloma, specifically an oral, active, well-tolerated PI.
January-February 2019Volume 16, Issue 1
A new Compendium providing updated clinical information to "Ask the Hematologist" articles published in The Hematologist from 2010 to 2015 is now available.
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by American Society of Hematology