Below you will find a collection of articles from Hematology, the ASH Education Program, written by experts in the field exploring topics such as personalized medicine, clinical trial design, and systematic reviews of medical literature, among others. A guide for patients about clinical trials, as well as links to other organizations that provide information on clinical trials, are also available. Patients and others are also encouraged to contact elected officials to encourage increased federal funding for scientific research.

Cellular Medicine

• Angiogenesis: A Target in Solid Tumors, Also in Leukemia? (2011) 
• Nurture versus Nature: The Microenvironment in Chronic Lymphocytic Leukemia (2011)  
• The Brain-Bone-Blood Triad: Traffic Lights for Stem-Cell Homing and Mobilization (2010) 
• Telomere Biology and Telomere Diseases: Implications for Practice and Research (2010) 
• Novel Insights into the Biology of CLL (2010) 
• Prognostic Markers and Stratification of Chronic Lymphocytic Leukemia (2010) 

Markers / Diagnostics

• New Prognostic Markers in Acute Myeloid Leukemia: Perspective from the Clinic (2010) 
• Tumor-Specific Genetic Lesions and Their Influence on Therapy in Pediatric Acute Lymphoblastic Leukemia (2006) 
• Deeper Insights into Hematological Oncology Disorders via Single-Cell Phospho-Signaling Analysis (2006) 

Molecular Medicine

• Atypical Hemolytic Uremic Syndrome, Genetic Basis, and Clinical Manifestations (2011) 
• Genomics of AML: Clinical Applications of Next-Generation Sequencing (2011) 
• The Yin and Yang of Stem Cell Gene Therapy: Insights into Hematopoiesis, Leukemogenesis, and Gene Therapy Safety (2007) 
• Update on Progress and Hurdles in Novel Genetic Therapies for Hemophilia (2007) 
• RNAi and Gene Therapy: A Mutual Attraction (2007) 
• Deeper Insights into Hematological Oncology Disorders via Single-Cell Phospho-Signaling Analysis (2006) 

Therapeutics

• Alternative Strategies for Gene Therapy of Hemophilia (2010) 
• Hemophilia: New Protein Therapeutics (2010) 
• Overview of Gene Therapy Clinical Progress Including Cancer Treatment With Gene-Modified T Cells (2009) 
• Ten Years of Gene Therapy for Primary Immune Deficiencies (2009) 
• Hematopoietic Stem Cell Gene Transfer for the Treatment of Hemoglobin Disorders (2009) 

Scientific and Clinical Trials Methodology

• Introduction to Surrogates and Evidence-Based Mini-Reviews (2009) 
• Are There Circumstances in Which Phase 2 Study Results Should Be Practice-Changing? (2007) 
• Trials and Tribulations of Systematic Reviews and Meta-Analyses (2007) 

Nanotechnology

• Application of Semiconductor and Metal Nanostructures In Biology and Medicine (2009) 
• Dendrimer-Based Nanoparticles for Cancer Therapy (2009) 
• Imaging Circulating Cells and Lymphoid Tissues With Iron Oxide Nanoparticles (2009) 

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