The American Society of Hematology Honors J. Evan Sadler, MD, PhD, with the 2018 Exemplary Service Award
Published on: October 15, 2018
15, 2018) – The American Society of Hematology (ASH) will recognize J. Evan
Sadler, MD, PhD, with the 2018 Exemplary Service Award for his exceptional
years of service and dedication to ASH and to hematology.
The Exemplary Service Award was established in 1998 to recognize an individual
whose outstanding service, extending over a period of years, has significantly
advanced the interests of the Society. The award will be given to Dr. Sadler
today by ASH Executive Director Martha Liggett, Esq., and Blood Deputy
Editor and ASH Past President Nancy Berliner, MD, at a symposium in his honor
at Washington University School of Medicine in St. Louis.
ASH President Alexis Thompson, MD, PhD, will present this award during the 60th
ASH Annual Meeting and Exposition this December in San Diego, California.
“The hematology community is grateful for Dr. Sadler’s many contributions
throughout his career. Not only has he accomplished a great deal in advancing
our understanding of bleeding and clotting disorders, but he has also generously
given his time to mentoring the next generation of researchers and educators,
peer review, and holding numerous leadership positions at ASH,” said Dr. Thompson.
who has served on the Washington University faculty for 34 years, pioneered the
study of several blood coagulation factors. In particular, his contributions
have been critical to the molecular, genetic, and biochemical characterization
of von Willebrand factor and ADAMTS13, two proteins associated with bleeding
and clotting disorders. His laboratory identified the molecular basis for a
range of subtypes of the bleeding disorder von Willebrand disease (VWD), which
has led to improved diagnosis and therapy. In addition, his complementary
studies of ADAMTS13 structure and function have important implications for
understanding the pathophysiology of thrombotic thrombocytopenic purpura, a
rare clotting disorder. The molecular understanding of these diseases
enabled Dr. Sadler to lead efforts to develop existing clinical guidelines for
the diagnosis and treatment of VWD and TTP. He currently serves as director of
the hematology division at Washington University, where he is also a professor
of medicine and of biochemistry and molecular biophysics.
has previously been recognized by the ASH membership for his contributions to
hematology. In 2016, Dr. Sadler received the Society’s Henry M. Stratton Medal
for Basic Science, which honors a senior investigator whose contributions to
basic hematology research are well recognized and have taken place over a
period of several years. In 1998, he received the William Dameshek Prize, which
is given to a hematologist in the early stages of his or her career who has
made outstanding contributions to hematology.
been a dedicated member of ASH throughout his career, serving as a councillor
from 1998 to 2002, treasurer of the Society from 2003 to 2006, and president in
2011. Dr. Sadler served as an associate editor of Blood from 1993 to 2002 as well as on the editorial board, and he has
published more than 60 papers in the journal. He was a scientific program co-chair
for the 50th ASH Annual Meeting and Exposition in 2008 and has also served on the
Committee on Investment and Audit, the Nominating Committee, the Society’s
taskforce on recruitment and retention to hematology, and scientific committees
on biochemistry, bleeding disorders, and platelet disorders. Dr. Sadler was
also involved in ASH’s first step into Asia as a speaker for the 2011
Highlights of ASH meeting in China; he also spoke at the first Highlights of
ASH meeting that same year in Uruguay. Colleagues have noted that his care in
supporting the future of hematology is apparent in his insightful and
thoughtful participation in study sections for ASH awards that promote the
careers of hematologists.
earned his PhD in biochemistry and his MD from Duke University in 1978 and
1979. He completed his postgraduate internship at Duke University before
heading to the University of Washington in Seattle to complete his fellowship.
He began his academic career at Washington University in St. Louis in 1984.
addition to his dedicated volunteerism with ASH, Dr. Sadler has served on and
chaired study sections at the National Institutes of Health and the
International Society on Thrombosis and Haemostasis (ISTH). His most
distinguished honors in addition to those from ASH include the Investigator
Recognition Award and Distinguished Career Award from ISTH and election to the
National Academy of Medicine. In addition to his numerous research and
leadership accolades, Dr. Sadler is known as an extraordinary mentor, having
trained a number of the key world leaders in academic hematology, particularly
American Society of Hematology (www.hematology.org) is the world’s largest professional society
concerned with the causes and treatment of blood disorders. Its mission is to
further the understanding, diagnosis, treatment, and prevention of disorders
affecting blood, bone marrow, and the immunologic, hemostatic, and vascular
systems by promoting research, clinical care, education, training, and advocacy
in hematology. The official journal of ASH is Blood (www.bloodjournal.org), the most cited peer-reviewed publication in
the field, which is available weekly in print and online. In 2016, ASH
launched Blood Advances (www.bloodadvances.org), an online, peer-reviewed open-access journal.
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Sara Khalaf, American Society of Hematology