American Society of Hematology

Schedule and Program

Please note: the following information is preliminary and subject to change.

Thursday, August 2, 2018

2:00 p.m. - 7:00 p.m.Registration
5:00 p.m. – 5:20 p.m.Welcome, Introduction, and Announcements

Riccardo Dalla-Favera, MD, Columbia University
Program Co-Chair

Kojo S.J. Elenitoba-Johnson, MD, University of Pennsylvania
Program Co-Chair

Freda K. Stevenson, DPhil, University of Southampton Medical School
Program Co-Chair
5:20 p.m. – 6:05 p.m.Opening Keynote Address: B Cell Antigen Receptor Signaling of Normal and Transformed B Cells

Michael Reth, PhD, University of Freiburg
6:05 p.m. – 8:00 p.m.Welcome Reception and Exhibits
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Friday, August 3, 2018

7:00 a.m. – 5:00 p.m.Registration
7:00 a.m. – 8:00 a.m.Breakfast and Exhibits
8:00 a.m. – 10:00 a.m.The Germinal Center as the Target Site

Chair:

Riccardo Dalla-Favera, MD, Columbia University

Speakers:

Jason Cyster, PhD, University of California – San Francisco Medical Center
Role of Cytokines in Germinal Center Development

Klaus Rajewsky, MD, The Max Delbrück Center for Molecular Medicine
Germinal Center Role in Lymphoma Tumorgenesis

Carola Vinuesa, MD, PhD, Australian National University College of Medicine
Germinal Center Biology
10:00 a.m. – 10:15 a.m.Networking Coffee Break
10:15 a.m. – 12:15 p.m.Microenvironment Influences in Lymphoma

Chair:

Freda K. Stevenson, DPhil, University of Southampton Medical School

Speakers:

Hans-Guido Wendel, MD, Memorial Sloan Kettering Cancer Center
Genetic Base Interaction of Microenvironment

Karin Tarte, PhD, INSERM U1236 & CHU Rennes
Follicular Lymphoma Microenvironment: Role in Pathogenesis and Clinical Impact

Ron Levy, MD, Stanford School of Medicine
Combining Intratumoral Injections of Toll-Like Receptor Agonists With Checkpoint Antibodies
12:15 p.m. – 1:15 p.m.Lunch and Exhibits
1:15 p.m. – 1:45 p.m.Company Presentations
1:45 p.m. – 4:00 p.m.Continuing Conversations
4:00 p.m. – 5:30 p.m.Poster Presentations
5:30 p.m. – 7:00 p.m.Dinner (provided)
7:00 p.m. – 9:00 p.m.Genetics and Epigenetics

Chair:

Ari Melnick, MD, Weill Cornell Medical College

Speakers:

Ari Melnick, MD, Weill Cornell Medical College
Epigenetics in Lymphoma

Laura Pasqualucci, MD, Columbia University
Genetic Basis of Epigenetics in Lymphoma

Suzanne Cory, Walter and Eliza Hall Institute of Medical Research
From Translocation to Therapy: How Understanding the BCL-2 Cell Life/Death Switch Is Leading to More Effective Therapy
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Saturday, August 4, 2018

7:00 a.m. – 5:00 p.m.Registration
7:00 a.m. – 8:00 a.m.Breakfast and Exhibits
8:00 a.m. – 9:45 a.m.New Technologies and Diagnostics

Chair:

Ash A. Alizadeh, MD, PhD, Stanford University Medical Center

Speakers:

Garry P. Nolan, PhD, Stanford University School of Medicine
Single Cell Analysis of Signaling

Ronald N. Germain, MD, PhD, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Single Cell Imaging

Ash A. Alizadeh, MD, PhD, Stanford University Medical Center
Circulating Tumor DNA
9:45 a.m. – 10:00 a.m.Networking Coffee Break
10:00 a.m. – 12:00 noonMolecular Targeting

Chair:

Louis Staudt, MD, PhD, National Cancer Institute, National Institutes of Health

Speakers:

Anthony Letai, MD, PhD, Dana-Farber Cancer Institute
Mitochondria Tell You What You Need to Know to Treat Lymphoid Cancers

Andreas Strasser, MSc, PhD, FAA, Walter and Eliza Hall Institute of Medical Research
Toward Targeting the Pro-Survival BCL-2 Family Members for Cancer Therapy

Roberto Chiarle, MD, Boston Children's Hospital
Targeted Therapy and Resistance in Lymphoma
12:00 noon – 1:00 p.m.Lunch and Exhibits
1:00 p.m. – 1:30 p.m.Company Presentations
1:30 p.m. – 3:15 p.m.Molecular Targeting (cont’d)

Chair:

Margaret A. Shipp, MD, Dana-Farber Cancer Institute

Speakers:

Louis Staudt, MD, PhD, National Cancer Institute, National Institutes of Health
B-Cell Receptor Targeting

Margaret A. Shipp, MD, Dana-Farber Cancer Institute
Checkpoint Inhibitors

Renier J. Brentjens, MD, PhD, Memorial Sloan Kettering Cancer Center
CAR T-Cell Therapy
3:15 p.m. – 3:45 p.m.Networking Coffee Break
3:45 p.m. – 5:15 p.m.Poster Presentations
5:15 p.m. – 6:45 p.m.Dinner (provided)
6:45 p.m. -  8:45 p.m.T-Cell Lymphoma

Chair:

Kojo S.J. Elenitoba-Johnson, MD, University of Pennsylvania

Speakers:

Laurence L. de Leval, MD, PhD, Lausanne University Hospital
Pathology and Genetic Lesions

Teresa Palomero, PhD, Columbia University
Peripheral T-Cell Lymphoma

Megan Lim, MD, PhD, University of Pennsylvania Perelman School of Medicine
Novel Insights Into Anaplastic Lymphoma Kinase-Mediated Pathogenetic Mechanisms in Anaplastic Large Cell Lymphoma
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Sunday, August 5, 2018

7:00 a.m. – 1:00 p.m.Registration
7:00 a.m. – 8:00 a.m.Breakfast and Exhibits
8:00 a.m. – 10:00 a.m.B-Cell Malignancies

Chair:

Catherine J. Wu, MD, Dana-Farber Cancer Institute

Speakers:

Bertrand Nadel, PhD, Centre D'Immunologie De Marseille-Luminy
Integrative Single-Cell Analysis: A New Prism to Decipher Follicular Lymphoma Heterogeneity

Ralf Kuppers, PhD, University of Duisburg - Essen
Hodgkin Lymphoma

Elias Campo, MD, PhD, University of Barcelona
Molecular Heterogeneity in Mantle Cell Lymphoma
10:00 a.m. – 10:20 a.m.Networking Coffee Break
10:20 a.m. – 10:50 a.m.Company Presentations
10:50 a.m. – 12:50 p.m.Chronic Lymphocytic Leukemia

Chair:

Elias Campo, MD, PhD, University of Barcelona

Speakers:

Francesco Forconi, MD, PhD, University of Southampton
B-Cell Receptor-Associated Kinase Inhibitors in Chronic Lymphocytic Leukemia

Catherine J. Wu, MD, Dana-Farber Cancer Institute
Clonal Heterogeneity

Davide Rossi, MD, PhD, Oncology Institute of Southern Switzerland
The Clinical Implications of Gene Mutations in Chronic Lymphocytic Leukemia
12:50 p.m. – 1:10 p.m.Closing Remarks

Riccardo Dalla-Favera, MD, Columbia University
Program Co-Chair

Kojo S.J. Elenitoba-Johnson, MD, University of Pennsylvania
Program Co-Chair

Freda K. Stevenson, DPhil, University of Southampton Medical School
Program Co-Chair
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