In a continuing effort to improve and enhance the ASH annual meeting experience and offerings, each year the Society adds new sessions and programs. Attendees should take note of the new, expanded, or enhanced existing offerings listed below that are making their debut at this year's annual meeting.
Featured Topic Discussion Sessions
Don't miss the new "Featured Topic Discussion Sessions" on Hemostasis and Thrombosis (Sunday, 11:15 a.m.) and Chimeric Antigen Receptors (Monday, 12:15 p.m). In these special hour-long sessions, invited discussants will discuss why the topic area is "hot" and analyze 8-12 abstracts of interest.
Special Symposium on Innovation and the Future of Hematology
Sunday, December 8, 1:00 p.m.- 2:30 p.m.
Janis L. Abkowitz, MD
President, American Society of Hematology, University of Washington
Stuart H. Orkin, MD
Howard Hughes Medical Institute, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School
Molecular Hematopoiesis: Single Genes to Many Genes and Beyond
Bruce A. Beutler, MD
University of Texas Southwestern Medical Center
Understanding Immunity by Making It Fail
This Special Symposium features two outstanding translational scientists, both innovative thinkers and engaging speakers, who will discuss how novel concepts and technologies should revolutionize hematology in the future.
Dr. Orkin will speak on the systems biology of normal blood cell differentiation and discuss how genomics and other new technologies may impact our understanding of hematologic disease pathogenesis and lead to novel therapies.
Dr. Beutler will speak on the importance of innate immunity and how understanding and harnessing the power of the immune system might impact hematology in the future.
Friday Scientific Workshop on Myeloid Development
Friday, December 6, 1:00 p.m. - 7:00 p.m.
Alan Hall Rosmarin, MD
University of Massachusetts Medical School
Leonard Zon, MD,
Howard Hughes Medical Institute, Children's Hospital Boston
All are invited to this workshop on the molecular and cellular mechanisms of myeloid development. This is a true workshop, where each section leader will briefly summarize the current questions facing the field and then lead discussions on how best to answer those questions. New findings or novel techniques that provide insight into these questions will be an essential part of this discussion. There is no additional fee to attend this workshop.
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Special Symposium on Approaches for Inhibiting "Undruggable" Targets in Cancer
Saturday, December 7, 4:00 p.m.- 5:30 p.m.
Kevin Shannon, MD
University of California- San Francisco
San Francisco, CA
Scott W. Lowe, PhD
Memorial Sloan- Kettering Cancer Center
New York, NY
Strategies for Targeting Mutant p53
Julian Downward, PhD
Cancer Research UK
London, United Kingdom
Synthetic Lethal Approaches for Targeting Mutant KRAS
Inhibitors that directly target cancer-associated mutant proteins frequently induce genotype-specific clinical responses. However, the most prevalent mutations found in cancer either disable tumor suppressor genes or encode oncogenic proteins with biochemical properties that are not amenable to chemical inhibition. Data from the Human Cancer Genome Atlas project and other large-scale sequencing efforts have shown that TP53 and KRAS are the most commonly mutated genes in human cancer. This session will address emerging strategies for therapeutically targeting p53 and oncogenic RAS in hematologic and non-hematologic cancers.
Dr. Scott Lowe will address the role of p53 in coordinating cellular stress responses and maintaining genomic integrity as well as approaches for treating cancers with TP53 mutations.
Dr. Julian Downward will review biochemical properties of the oncogenic RAS/GTPase activating protein (GAP) molecular switch, potential strategies for treating cancers with somatic RAS gene mutations, and the use of synthetic lethal screens to uncover vulnerabilities that can be targeted therapeutically.
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Special Symposium on Redox in Hematology
Sunday, December 8, 9:30 a.m. - 11:00 a.m.
José López, MD
Puget Sound Blood Center, University of Washington
Steven Lentz, MD, PhD
The University of Iowa
Iowa City, IA
Redox Regulation of Hemostasis
Katya Ravid, PhD, DSc
Redox Regulation of Megakaryopoiesis and Platelet Function: The Role of Lysyl Oxidase
Joseph Loscalzo, MD, PhD
Brigham and Women's Hospital
Redox and the Vessel Wall
The influence of reduction/oxidation chemistry in hematology and in many other areas of biology and medicine, particularly the role of oxidation, is poorly understood and underappreciated. For example, oxidation is generally considered to be harmful with nonspecific effects; however, many of its effects are actually very specific and often necessary for normal function. In this session, the role of redox chemistry in three areas of hematology will be discussed. The three talks will share the common theme of how protein and cellular functions relevant to hematology are regulated by specific electron-transfer reactions.
Dr. Steven Lentz will cover the role of redox in regulating hemostasis and thrombosis.
Dr. Katya Ravid will discuss how reactive oxygen species influence hematopoiesis and thrombosis, including her own work on lysyl oxidase in megakaryopoiesis and platelet function.
Dr. Joseph Loscalzo will discuss the role of redox switches in regulating vascular function.
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Special- Interest Session:"How to Get Published in a Peer- Reviewed Journal" (formerly a Trainee Didactic Session)
Sunday, December 8, 11:15 a.m.- 12:15 p.m.
Bob Lӧwenberg, MD, PhD
Editor-in-Chief, Blood, Erasmus Medical Center
The ability to communicate one's work effectively by publication in high impact journals is a benchmark for success in academic medicine. Even high-quality work may not be accepted if not presented in a well-crafted manuscript. This talk will provide insight into the elements of a high-quality manuscript worthy of publication in Blood, and tips on avoiding common errors that might result in rejection.
American Board of Internal Medicine Maintenance of Certification Learning Session
Friday, December 6, 2:00 p.m.- 5:00p.m.
Adam Cuker, MD, MS
University of Pennsylvania
Paul Barr, MD
University of Rochester
Lucy Godley, MD, PhD
The University of Chicago
Adam Cuker, MD, MS
University of Pennsylvania
This Maintenance of Certification (MOC ) Learning Session will feature an American Board of Internal Medicine (ABIM) medical knowledge module on hematology; it is intended for those who are enrolled in the MOC process and due to recertify in the next few years. Learning Sessions are conducted in an interactive group setting and are led by ABIM-certified physicians. The three-hour session will cover the 30 multiple-choice questions in the "2013 Update in Hematology" ABIM module.
At the completion of this session, those enrolled in the ABIM MOC program can submit their answers to ABIM for scoring to receive MOC credit. Enrolled participants can order a copy of the module(s) online from ABIM's website. At the conclusion of the session, participants will transfer the answers to their online module and submit the module to ABIM for scoring. For additional information about ABIM's MOC program requirements, visit the ABIM website or call the ABIM Contact Center at 800- 441-ABIM. Please note that this is not a board review activity; the workshop is designed to facilitate completion of ABIM's Self-Evaluation of Medical Knowledge MOC requirement.
Associate Member: $50
Non-Member in Training: $85
Tickets can be purchased online during the meeting registration process.
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ASH Practice Partnership Lunch (APP)
Sunday, December 8, 11:15 a.m.- 12:30 p.m.
Health Reform Implementation in 2014- What Can Hematologists Expect?
Steven L. Allen, MD
North Shore- Long Island Jewish Health System
Lake Success, NY
Kavita Patel, MD
The ASH Practice Partnership (APP) is ASH's network for practice-based hematologists to elevate practice-related issues within the Society. The APP Lunch is a special session during the annual meeting designed for this community. During the first half of this session, attendees will hear from a national policy expert to obtain an "insider's" view of the major provisions of the Patient Protection and Affordable Care Act (PPACA) taking effect in 2014.
The presentation will include an overview of the expansion of Medicaid, the development of state insurance exchanges for individuals and small businesses, and other private health insurance plan reforms that will impact physicians. Participants will also receive a description of ASH resources to help hematologists during PPACA implementation. The second half of the session will provide a networking opportunity for practice-based hematologists to meet with colleagues and ASH leaders.
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Scientific Program Session on Epigenetics and Genomics
Saturday, December 7, 2:00 p.m.- 3:30 p.m.
Sunday, December 8, 9:30 a.m.- 11:00 a.m.
Ross Levine, MD
Memorial Sloan Kettering Cancer Center
New York, NY
Kristian Helin, PhD
University of Copenhagen
TET Proteins and Histone Modifications in Hematopoiesis
Brian J.P. Huntly, MD, PhD
University of Cambridge
Cambridge, United Kingdom
Role of Epigenetic Readers in Pathogenesis and Therapy of Acute Leukemias
Robert A. Copeland, PhD
Protein Methyltransferase Inhibitors as Personalized Cancer Therapeutics
This session will focus on the role of epigenetic modifications in normal and malignant hematopoiesis, including recently described DNA and histone modifications that affect gene expression, self-renewal, and transformation.
It will begin with discussion of recent studies of DNA modifications and alterations in histone state and how these alterations affect gene expression and hematopoietic function. Subsequent talks will focus on how alterations in these epigenetic modifications contribute to disease states and how epigenetic alterations in hematologic malignancies have led to the identification and validation of novel therapeutic targets.
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Scientific Spotlight Sessions
This year ASH will offer Scientific Spotlight Sessions on four exciting topics. Each 90-minute session will be presented once on either Sunday or Monday in a small-venue format for approximately 150 ticketed attendees.
Speakers will discuss the topic with ample time reserved for audience questions and participation. The talks will facilitate discussions of evidence-based practice, decision making, and controversies in diagnosis and management. The lectures will address the current state of knowledge, translational and clinical applications, and future directions.
Ticket Prices (per session)
Associate Member: $25
Medical Student, Graduate Student, or Resident Member: $25
Non-Member in Training: $25
Allied Health Professional: $35
The Scientific Spotlight Sessions are restricted to medical professionals only; no businesspersons or media will be admitted. Individuals are limited to one ticket per session. Tickets may be purchased during the online registration process.
A number of tickets for the Scientific Spotlight Sessions will be reserved especially for trainees. Proof of status as an Associate member; Medical Student, Graduate Student, or Resident member; or non-member in training will be required to purchase a ticket. Please show your name badge to the staff at the Ticketed Sessions counter at the registration area in the Great Hall of the Ernest N. Morial Convention Center.
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Continuing Conversations (formerly Scientific Forums)
Saturday, December 7, 11:15 a.m. - 12:15 p.m.
Continuing Conversations sessions are informal discussions with scientific program session speakers that will give interested individuals, especially trainees and junior investigators, increased accessibility both to information on the topic and to the opinions of experts in those particular fields. The dynamic nature of these sessions is meant to provide an increased opportunity for scientific peers to form collaborations and partnerships. The format of these sessions is a roundtable discussion for a limited audience of 40 participants. Attendees should come prepared to actively participate in the discussions.
Continuing Conversations sessions are restricted to medical professionals only; no businesspersons or media will be admitted. Tickets are limited and only available on site on a first-come, first-served basis. There is no additional fee; however, only one ticket per person is allowed. Tickets are sold on site at the Ticketed Sessions Counter at the registration area in the Great Hall of the Ernest N. Morial Convention Center.
Multiple seating areas with tables and chairs will be placed throughout the convention center to enable attendees to meet one another for informal, impromptu conversations and small meetings. Look for "Hematology MeetUp" area designated on the convention center map to find the nearest location.
Live Remote Session Viewing Lounge
New seating areas located at each end of the convention center will enable attendees to experience sessions located across the convention center without having to walk the long distance from one end to the other. Each remote session viewing lounge will have television monitors/screens displaying the slides from a selection of sessions located in the opposite end of the building. Participants will be provided with a set of headphones so they may listen to the selected speaker. Note: Not all sessions will be broadcast into the remote session viewing lounges.
Two Poster Halls
This year's meeting will include two poster halls; halls E and G. Please see the final online program for more information.
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