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Readers of TraineE-News know that a recurring feature of the newsletter is a board-style question with an explanation and a link to a relevant article. We changed it up this time and published an image challenge.
What is the most common cytogenetic abnormality predicted by this bone marrow aspirate?
These abnormal eosinophils with basophilic inclusions ("eo-basos") have been associated with acute myeloid leukemia with the inversion 16 cytogenetic abnormality.1
1. Le Beau MM, Larson RA, Bitter MA, et al. Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association. N Engl J Med. 1983. 309:630-636.
Access an extensive online library of screen-sized blood disease images and cases for educational use.
A new Compendium providing updated clinical information to "Ask the Hematologist" articles published in The Hematologist from 2010 to 2015 is now available.
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by American Society of Hematology