American Society of Hematology

Outstanding Abstract Achievement Awards

2017 Recipients

Undergraduate Student
Kacey Guenther
National Institutes of Health
Eltrombopag Promotes DNA Repair in Human Hematopoietic Stem and Progenitor Cells: Implications for the Treatment of Fanconi Anemia
Abstract #776

Medical Student
Diego Espinoza
National Institutes of Health
Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque
Abstract #606

Graduate Student
Shuhei Asada
The Institute of Medical Science, The University of Tokyo
Mutant ASXL1 Cooperates With BAP1 to Promote Myeloid Leukemogenesis
Abstract #562

Resident Physician
Simon Heidegger, MD
Klinikum rechts der Isar, Technical University Munich
Tumor-Intrinsic RIG-I Signaling Promotes Anti-CTLA-4 Checkpoint Inhibitor-Mediated Anticancer Immunity
Abstract #693

Post-Doctoral Fellow
Franco Izzo, PhD
New York Genome Center
Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation
Abstract #559

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2016 Recipients

UNDERGRADUATE STUDENT
Ryunosuke Saiki
Kyoto University
NGS-Based Copy Number Analysis in 1,185 Patients with Myeloid Neoplasms 
Publication #955

MEDICAL STUDENT
Matthew Hartwell
Icahn School of Medicine at Mount Sinai
An Early Biomarker Algorithm Predicts Lethal Graft-Versus-Host Disease and Survival after Allogeneic Hematopoietic Cell Transplantation 
Publication #509

GRADUATE STUDENT
Xiaotian Zhang
Baylor College of Medicine
High Order Chromatin Structure Regulates Gene Expression in Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation
Publication #1033

RESIDENT PHYSICIAN

Maximilian Witzel, MD
Ludwig-Maximilians-Universität München
SWI/SNF Protein SMARCD2 Orchestrates Transcriptional Networks Controlling Hematopoiesis and Neutrophil Granulocytes in Humans, Mice and Zebrafish
Publication #2

POST DOCTORAL FELLOW
Ly Vu, PhD
Memorial Sloan Kettering Cancer Center
RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program

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2015 Recipients

Undergraduate Student
Hannah Rasmussen
Harvard University, Cambridge, MA
Oncostatin M Enhances Hematopoietic Stem Cell Homing and Engraftment
Publication #31

Medical Student
Bryan Harris
Fox Chase Cancer Center, Philadelphia, PA
Rpl22 Deficiency Predisposes Hematopoietic Stem and Progenitor Cells to Leukemogenesis
Publication #899

Graduate Student
Lars Klemm, MSc
University of California – San Francisco, San Francisco, CA
Exposure to Inflammatory Immune Responses As Driver of Clonal Evolution in Childhood Acute Lymphoblastic Leukemia
Publication #166

Resident Physician
Ryan Moy, MD, PhD
University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
Immunologic Effects of CCR5 Blockade in Graft-Versus-Host Disease Prophylaxis
Publication #920

Post-Doctoral Fellow
Noboru Asada, MD, PhD
Albert Einstein College of Medicine, New York, NY
Distinct Contributions By Perivascular Niche Cells in Hematopoietic Stem Cell Maintenance
Publication #661

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2014 Recipients

Undergraduate Student
Kathryn Luk
University of Minnesota, Minneapolis, MN
Mast Cell Activation in Sickle Mice Stimulates Endothelial Dysfunction
Publication #453

Medical Student
Joshua Siner
Children’s Hospital of Philadelphia, Philadelphia, PA
Unexpected Role of PACE/Furin Cleavage Site in FVIII Biology: Implications for Hemophilia A Therapy
Publication #105

Graduate Student
Noemi Zambetti
Eramus University Medical Center, Rotterdam, Netherlands
Deletion of Sbds from Hematopoietic Progenitors Causes Neutropenia in a Mouse Model of Shwachman-Diamond Syndrome By Specifically Blocking Myeloid Lineage Progression at Late Differentiation Stages
Publication #355

Resident Physicians
Jurjen Versluis
Erasmus University Medical Center, Rotterdam, Netherlands
The Comparative Value of Hematopoietic Stem Cell Transplantation and Chemotherapy in Cytogenetically Normal AML Subclassified By NPM1 Mutation Status and FLT3-ITD Allelic Ratio
Publication #323

Raynier Devillier
Institut Paoli Calmettes, Marseille, France
Higher Doses of Antithymocyte Globulin (ATG) Increase the Risk of Relapse in Acute Myeloid Leukemia (AML) Patients Undergoing Matched Related Donor Allogeneic Transplantation in First Complete Remission (CR1): An Analysis from the Acute Leukemia Working Party of EBMT
Publications #729

Post Doctoral Fellow
Léon Kautz, PhD (Joanne Levy, MD, Memorial Award for Outstanding Achievement recipient at 2014 ASH Annual Meeting)
University of California-Los Angeles, Los Angeles, CA
Role of Erythroferrone in the Pathophysiology of Common Anemias
Publications #213

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2013 Recipients

Undergraduate Students
Meredith Fay
Georgia Institute of Technology and Emory University, Atlanta, GA
White Blood Cell Mechanics Mediate Glucocorticoid- and Catecholamine-Induced Demargination
Publication #3495

Ruben Land
Columbia University, New York, NY
The Orphan Nuclear Receptor Nr4a1 Specifies Long-Term, Myeloid-Biased HSCs and Responds To PGE2
Publication #3675

Medical Student
Anna Mertelsmann
Memorial Sloan-Kettering Cancer Center, New York, NY
IL-22 Administration Decreases Intestinal GVHD Pathology, Increases Intestinal Stem Cell Recovery, and Enhances Immune Reconstitution Following Allogeneic Hematopoietic Transplantation
Publication #290

Graduate Student
Jonathan Reichel
Weill Cornell Medical College, New York, NY
Exome Sequencing of Purified Hodgkin Reed-Sternberg Cells Reveals Recurrent Somatic Mutations In Genes Responsible for Antigen Presentation, Chromosome Integrity, Transcriptional Regulation and Protein Ubiquitination
Publication #625

Resident Physician
Kaan Boztug, MD
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
Deficiency of JAGN1 Causes Severe Congenital Neutropenia Associated With Defective Secretory Pathway and Aberrant Myeloid Cell Homeostasis
Publication #439

Post Doctoral Fellow
Léon Kautz, PhD
University of California – Los Angeles, Los Angeles, CA
The Erythroid Factor Erythroferrone and Its Role In Iron Homeostasis
Publication #4

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2012 Recipients

Undergraduate Student
Pranam Chatterjee
PD-1 Couples Glucose Starvation with Autophagy and Survival Through AMPK-Mediated Phosphorylation of Ulk1
Abstract #836

Medical Student
Thibault Dupont
Combinatorial Targeting of BCL6 and Anti-Apoptotic Proteins in Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma (FL)
Abstract #64

Graduate Students
Steven Rhodes
Haploinsufficiency of Nf1 in Myeloid Lineages Contributes to Neurofibromatosis Type 1 Associated Skeletal Deficits
Abstract #830

Kenichi Yoshida, MD
Genetic Basis of Myeloid Proliferation Related to Down Syndrome
Abstract #535

Resident Physicians
Jan-Henning Klusmann, MD
the miR-99~125 Polycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling
Abstract #109

Hanna L.M. Rajala, MD
Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia
Abstract #871

Postdoctoral Fellows
Xavier Anguela, PhD
In Vivo Genome Editing of Liver Albumin for Therapeutic Gene Expression: Rescue of Hemophilic Mice Via Integration of Factor 9
Abstract #751

Raffaele Renella, MD, PhD
Hematopoietic SIN Lentiviral Micro RNA-Mediated Silencing of BCL11A: Pre-Clinical Evidence for a Sickle Cell Disease Gene-Therapy Trial
Abstract #753

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2010 Recipients

Undergraduate Student
Maria Virgilio
Treatment of Zebrafish Models of Ribosomopathies (Diamond Blackfan Anemia (DBA) and 5q- Syndrome) with L-Leucine Results In An Improvement of Anemia and Developmental Defects: Evidence for a Common Pathway?
Publication #195

Medical Student
Karrune Woan
Identification of a Discrete Subpopulation of T-Cells Over-Expressing HDAC11 with a TH17 Phenotype
Publication #588

Graduate Student
Wulan Deng
Manipulating Higher Order Chromatin Structure of the β-Globin Locus by Targeted Tethering of a “looping” Factor
Publication #647

Resident Physician
Kaan Boztug
Correction of Wiskott-Aldrich Syndrome by Hematopoietic Stem Cell Gene Therapy
Publication #5

Post Doctoral Fellow
Jian Xu, PhD
Reactivation of Silenced Human HbF In Adult Mice by Inactivation of BCL11A
Publication #643

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2009 Recipients

Undergraduate Student
Kimberly Fan
Emory University, Atlanta, GA
Donor Dendritic Cells Home to Lymphoid Organs in Allogeneic Transplant Recipients, Enhance Donor T-Cell Chimerism, and Polarize Donor T-Cell Activation

Medical Student
Kyle Eash
Washington University School of Medicine, Saint Louis, MO
­CXCR2 Signals Act in Concert with CXCR4 to Regulate Neutrophil Release From the Bone Marrow

Graduate Student
Hélène Moniz, MD
Institut Gustave Roussy, Villejuif, France
Distinct Differences in inVitro Erythroid Proliferation and Differentiation, p53 and Apoptosis Pathways in Diamond-Blackfan Anemia in Conjunction with Depletion of RPS19, RPL5 and RPL11 mRNA

An De Weer, MD
Ghent University Hospital, Belgium
Downregulation of MiR-449a Is Essential for the Survival of EVI1 Positive Leukemic Cells through Modulation of NOTCH1 and BCL2

Resident Physician
Suparna Nanua, MD, PhD
Washington University School of Medicine, Saint Louis, MO
Loss of PERK Signaling Results in Impaired Granulopoiesis in Transgenic Mice Expressing Mutant Ela2

Post Doctoral Fellow
Jian Xu, PhD
Children's Hospital Boston, Harvard Medical School, Boston, MA
Control of Hemoglobin Switching by BCL11A

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2008 Recipients

Undergraduate Students
Julie Boiko
Stanford University School of Medicine, Stanford, CA
IgG Allotypes Reveal That Antimicrobial Humoral Immunity Persists after Reduced-Intensity Hematopoietic Cell Transplantation

Katelyn Dow
The Cardiovascular Research Institute at UCSF, San Francisco, CA
A Novel Tissue Factor Resistance Locus on Mouse Chromosome 11 Confers Protection from Thrombosis through Reduced Activity of Factor XI

Medical Student
Robert Blue
The Rockefeller University, New York, NY
Limiting αIIb Extension at the Genu Differentially Affects Binding of Small and Large Ligands to αIIbβ3

Graduate Student
Christopher Miller
St. Jude Children's Research Hospital, Memphis, TN
Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia

Resident Physician
Kaan Boztug, MD
Hannover Medical School, Hannover, Germany
A Novel Clinical Syndrome Associating Severe Congenital Neutropenia and Complex Developmental Aberrations Caused by Deficiency of G6PC3

Post Doctoral Fellow
Simon Mendez-Ferrer, Ph.D
Mount Sinai School of Medicine, New York, NY
Mesenchymal Stem Cells, Regulated by the Sympathetic Nervous System, Form the Hematopoietic Stem Cell Niche

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2007 Recipients

Undergraduate Student
Aditya Mandawat
Pan-Histone Deacetylase (HDAC) Inhibitor LBH589 Depletes CXCR4 Levels and Signaling, Exerting Synergistic Anti-Leukemia Activity in Combination with CXCR4 Antagonists
Publication #537

Shailaja Karanti
An Atlas of the MicroRNA Genome in Human DLBCL
Publication # 563

Medical Student
Andrew McDaniel
Loss of Pak1 Corrects Multiple Gain of Function Phenotypes in Nf1+/- Mast Cells
Publication # 236

Joshua H. Wong, BS, MS
Increased Thrombosis in Male Versus Female Mice Is Mediated by Pulsatile Growth Hormone Secretion Possibly through Inhibition of TFPI Expression in the Vasculature
Publication # 266

Graduate Student
Gustavo F. Da Silva, MS
Design and Development of Small Molecules for Specific Targeted Therapy of Diffuse Large B-Cell Lymphoma
Publication # 799

Resident Physician
Claudia Lengerke, MD
BMP and Wnt Induce Embryonic Blood Fate by Activation of the Cdx-Hox Pathway
Publication # 199

Post-Doctoral Fellow
Simon Mendez-Ferrer, PhD
Circadian Traffic of Hematopoietic Stem Cells Is Orchestrated by the Molecular Clock and Mediated by β3 Adrenergic Signals from the Sympathetic Nervous System
Publication # 219

Charles G. Mullighan, MBBS, MD
Oncogenes and Tumor Suppressors I
ERG Deletions Define a Novel Subtype of B-Progenitor Acute Lymphoblastic Leukemia
Publication # 691

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